Advanced Malignancies Clinical Trials

A listing of Advanced Malignancies medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 122 clinical trials
Balstilimab Versus Investigator Choice Chemotherapy in Patients With Recurrent Cervical Cancer (BRAVA)

This Phase 3 trial is an open-label, randomized study with single-agent Balstilimab (BAL) or Investigator Choice (IC) chemotherapy (single-agent gemcitabine, irinotecan, pemetrexed, vinorelbine, or topotecan) in patients with recurrent, persistent, or metastatic cervical cancer who have progressed after receiving platinum based chemotherapy.

  • 0 views
  • 18 Jul, 2021
  • 2 locations
Physical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Participants With Advanced Metastatic or Recurrent Cancer

The goal of this clinical research study is to learn about the effects of combining physical activity with dexamethasone to treat fatigue in patients with advanced cancer. In this study

cancer
delirium
advanced cancer
  • 1 views
  • 01 Aug, 2021
  • 1 location
A Study to Test Different Doses of BI 765063 Alone and in Combination With BI 754091 in Japanese Patients With Different Types of Advanced Cancer (Solid Tumors)

This study is open to Japanese adults with advanced cancer (solid tumors). This is a study in people for whom previous treatment was not successful and for whom no standard therapy exists. The

  • 0 views
  • 20 Jul, 2021
  • 4 locations
A Study to Test Different Doses of BI 3011441 in Japanese People With Different Types of Advanced Cancer (NRAS/KRAS Mutation Positive)

This study is open to Japanese adults with different types of advanced cancer that are positive for NRAS/KRAS mutations. This is a study in people for whom previous treatment was not successful

  • 0 views
  • 20 Jul, 2021
  • 3 locations
Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers

The primary objectives of Phase 1A are to evaluate the safety of KITE-718, determine a recommended Phase 1B dose, and to evaluate the efficacy of KITE-718 in Phase 1B.

metastasis
neutrophil count
cyclophosphamide
liver metastasis
alopecia
  • 48 views
  • 31 Jul, 2021
  • 16 locations
Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia

Study to compare the effects of the investigational new drug (PF-06946860) and a placebo on appetite and to find out how participants with advanced cancer and anorexia feel after receiving

cancer chemotherapy
cancer of the ovary
antineoplastic
cancer
megestrol acetate oral suspension
  • 0 views
  • 01 Aug, 2021
  • 40 locations
This Study Aims to Find the Best Dose of BI 907828 in Patients With Different Types of Advanced Cancer (Solid Tumors)

This study is open to adults with different types of advanced cancer (solid tumours). The purpose of this study is to find out the highest dose of BI 907828 the participants can tolerate

advanced cancer
solid neoplasm
primary cancer
TP53
measurable disease
  • 56 views
  • 21 Jul, 2021
  • 6 locations
A Study to Test Different Doses of BI 1810631 in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

The study has 2 parts. The first part is open to adults with different types of advanced cancer (solid tumours with changes in the HER2 gene) for whom previous treatment was not successful. The

EGFR
egfr t790m
neutrophil count
alopecia
growth factor
  • 0 views
  • 01 Aug, 2021
  • 1 location
A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation)

This is a study in adults with advanced cancer (solid tumours) in whom previous chemotherapy was not successful. Only people who have a tumour with a KRAS mutation can participate in the study

  • 11 views
  • 01 Aug, 2021
  • 7 locations
9-ING-41 in Pediatric Patients With Refractory Malignancies.

9-ING-41 has anti-cancer clinical activity with no significant toxicity in adult patients. This Phase 1 study will study its efficacy in paediatric patients with advanced malignancies.

pleural effusion
mibg
brain stem tumor
monoclonal antibodies
hematopoietic growth factors
  • 0 views
  • 01 Aug, 2021
  • 9 locations