Overactive Bladder Clinical Trials

A listing of Overactive Bladder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 57 clinical trials
A Two-part, Multicenter, Dose-titration Study Evaluating Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of Oxybutynin Chloride 10% Gel for Treatment of Detrusor Overactivity Associated Neurological Condition in Pediatric Patients

This study will evaluate the safety and efficacy of Oxybutynin Chloride 10% Topical Gel in children 3 to less than 17 years old, who have overactive bladder due to a neurogenic condition

overactive bladder
neurogenic bladder
oxybutynin
  • 96 views
  • 18 Oct, 2022
  • 5 locations
A Sham-Controlled Study to Evaluate the Safety and Efficacy of a Smart, Self-Adjusting, Surgery-Free, Wearable Bladder Neuromodulation System for Overactive Bladder (REDUCEOAB)

This is a prospective, multi-center, sham-controlled study comparing the safety and effectiveness of the self-adjusting, surgery-free, wearable Active System to a Sham System on adult Subjects diagnosed with OAB.

overactive bladder
micturition chart
bladder diary
neuromodulation
  • 0 views
  • 07 Jun, 2022
  • 1 location
Posterior Tibial Nerve Stimulation (PTNS) Plus Mirabegron to Treat Refractory OAB Symptoms (PTNS-M Study)

Abstract Introduction: Urgency Urinary Incontinence (UUI) is a common condition with a prevalence of 9-31% in women in the United States. Despite current treatments, a high number of women have symptoms refractory to first- and second-line treatment approaches. Aims: The primary aim of this randomized controlled trial is to compare …

mirabegron
incontinence
Accepts healthy volunteers
percutaneous tibial nerve stimulation
  • 0 views
  • 15 Dec, 2021
  • 1 location
Evaluation of Implantable Tibial Neuromodulation Pivotal Study (TITAN 2)

The purpose of this prospective, multicenter study is to assess the safety and efficacy of tibial neuromodulation using the Medtronic Tibial Neuromodulation (TNM) system.

conservative therapy
neuromodulation
  • 0 views
  • 21 Oct, 2022
  • 20 locations
Intradetrusor Botulinum Toxin A: Are Less Injections Better?

Patients with either overactive bladder (OAB) or urgency urinary incontinence (UUI) with be randomized (like a flip of a coin) to receive 100 units of bladder Botox® at either one injection site

onabotulinumtoxina
overactive bladder
incontinence
urinary urgency
Accepts healthy volunteers
  • 0 views
  • 07 Jun, 2022
  • 1 location
TENS Used for Pain Management During Office Cystoscopy Botox Injections

The purpose of this study is to determine how Transcutaneous Electric Nerve Stimulation (TENS) units affects pain management during office cystoscopic Botox injections and patient satisfaction with the procedure .

TENS
botox
transcutaneous electrical nerve stimulation
  • 10 views
  • 04 Oct, 2022
  • 1 location
Sham Controlled Trial of Rapid Induction Percutaneous Tibial Nerve Stimulation

The aim of this study is to determine the efficacy of an accelerated course for percutaneous tibial nerve stimulation (PTNS) induction to treat overactive bladder symptoms. The standard 12

bladder symptoms
antimuscarinic
percutaneous tibial nerve stimulation
  • 26 views
  • 28 Oct, 2022
  • 1 location
BOTOX at the Time of Prolapse Surgery for OAB

The purpose of the study will be to assess the efficacy and safety of bladder BOTOX for overactive bladder symptoms, such as urinary urgency and frequency, given at the time of prolapse surgery

intermittent catheterization
brimonidine tartrate ophthalmic solution
onabotulinumtoxina
bladder symptoms
urinary urgency
  • 0 views
  • 22 Oct, 2021
  • 1 location
Mechanisms for Activation of Beige Adipose Tissue in Humans

Mirabegron (Myrbetriq®, Astellas) is a highly specific and well-tolerated ß3 agonist marketed for overactive bladder. This trial will assess the effects of mirabegron on glucose tolerance and

Accepts healthy volunteers
fasting
impaired glucose tolerance
  • 283 views
  • 24 Mar, 2022
  • 1 location
Oxybutynin for Post-surgical Bladder Pain and Urgency

Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

oxybutynin
bladder surgery
  • 3 views
  • 25 Mar, 2022
  • 1 location