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Diabetes Mellitus Type 2 Clinical Trials

A listing of Diabetes Mellitus Type 2 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (123) clinical trials

A randomized, open-label, parallel group real world pragmatic trial to assess the clinical and health outcomes of Toujeo® compared to commercially available basal insulins for initiation of therapy in insulin naïve patients with uncontrolled type 2 diabetes mellitus.

Phase

The primary efficacy objective is to determine whether treatment with dapagliflozin compared with placebo when added to current background therapy will result in a reduction in the incidence of the composite endpoint of cardiovascular death, myocardial infarction (MI), or ischemic stroke in patients with type 2 diabetes mellitus (T2DM) with …

Phase

The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin compared with placebo, in addition to standard of care, in patients with type II diabetes mellitus and acute coronary syndrome. Patient Inclusion Criteria: In order to participate in this study you need to have a hgA1c level …

Phase

Dr. Paula Newton is conducting a study to determine whether a short period of exercise will lower blood sugars in teenagers and young adults with type 2 diabetes. This study includes 4 outpatient study visits over about 2 weeks. Two of the visits will take about an hour and two …

Phase

Do you have type 2 diabetes? A clinical research study is evaluating how an investigational medication may give you better control of your type 2 diabetes. To qualify, you must be between 18 and 80 years of age and taking metformin alone, or in combination with another oral diabetes drug …

Phase

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

As a consequence of the COVID-19 pandemic and after consultation with the appropriate research oversight, regulatory and monitoring entities, screening and enrollment has been placed on temporary administrative hold as of 3/17/2020. When such trial activities resume, the clinicaltrials.gov record will be updated accordingly. CSP #2002 is a multicenter, prospective, …

Phase

Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration

Hyperfiltration is a characteristic feature in experimental models of diabetes and is causally related to an increase in intraglomerular pressure. In newly diagnosed diabetic patients, both type 1 and type 2, hyperfiltration and enlarged kidney size commonly are observed, and these hemodynamic/anatomic abnormalities are associated with an increased risk for …

Phase

Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease

GLP-1 is an incretin hormone that mediates glucose-stimulated insulin secretion.Accumulating data from both animal and human studies confirmed a beneficial effect of GLP-1 on myocardium, endothelium and vasculature, suggesting the potential ameliorative effect of peripheral atherosclerosis. In our preliminary studies shown that liraglutide, a long-acting GLP-1R agonist (GLP1RA), stimulate endothelial …

Phase

Efficacy of Individualized Rituximab in Maintaining Remission of Moderate and Severe Systemic Lupus Erythematosus

Several clinical studies have shown that rituximab is safe and effective for the induction of remission in moderate to severe systemic lupus erythematosus, and has been recommended by several guidelines for the induction of remission in refractory lupus with important organ involvement. However, there are few studies on the use …

Phase