Nonalcoholic Steatohepatitis (NASH) Clinical Trials

A listing of Nonalcoholic Steatohepatitis (NASH) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 109 clinical trials
Effects of Dietary Nutrients on Liver and Adipose Tissue Metabolism

In health,adipose tissue stores fat from the diet. If the fat tissue stops storing dietary fat then this increases the chance of it being stored in the liver, which is related to increased risk of heart disease and type 2 diabetes. It has been suggested that having a diet high …

diabetes
Accepts healthy volunteers
type 2 diabetes mellitus
body mass index
sugars
  • 1 views
  • 17 Jun, 2022
  • 1 location
Whey or Casein - Liver Fat Reduction and Metabolic Improvement by Fast vs. Slow Proteins (MOCA)

High-protein diets have been recently demonstrated to effectively reduce insulin resistance, derangements of the lipid profile and liver fat content in subjects with moderately and severely impaired glucose metabolism and non-alcoholic fatty liver disease (LeguAN, LEMBAS, DiNA-P, DiNA-D). The effects can be attributed to prolonged insulin secretion and improved second …

Accepts healthy volunteers
  • 30 views
  • 04 Oct, 2022
  • 1 location
Quantitative Ultrasound With Liver Incytes for Evaluation of Non-Alcoholic Fatty Liver Disease

The purpose of this study is to prospectively evaluate the utility of Liver Incytes in assessing NAFLD with or without advanced fibrosis in patients seen in liver clinics for suspected NAFLD diagnosis.

  • 0 views
  • 24 Mar, 2022
  • 1 location
NASH and Coronary Disease (CORO-NASH)

Although the clinical relationship between NAFLD/NASH and cardiovascular (CV) risk is now well established, there is very little awareness of the hepatic disease and the way it may contribute to

liver disease
fibrosis
steatohepatitis
steatosis
  • 1 views
  • 07 Oct, 2022
  • 1 location
Genetic-specific Effects of Fructose on Liver Lipogenesis

The primary goal of this study is to identify a set of genotypes that increase the risk for nonalcoholic fatty liver disease (NAFLD) and predispose individuals to increased de novo lipogenesis (DNL) and liver fat accumulation when exposed to fructose intake. The proposed goal will be achieved through the completion …

Accepts healthy volunteers
fructose
liver disease
fatty liver
  • 0 views
  • 27 Apr, 2022
  • 1 location
Liver Health and Metabolic Function in People With Obesity

This project aims to determine the effect of significant weight loss on rates on hepatic fibrogenesis in people with obesity.

Accepts healthy volunteers
bariatric surgery
body mass index
  • 100 views
  • 04 Oct, 2022
  • 1 location
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

Background In non-alcoholic fatty liver disease (NAFLD), fat accumulates in the liver and can cause damage. Researchers want to learn what causes the damage NAFLD, and to see if a medication can help. Objective To find out how the liver in people with NAFLD responds to feeding, and how this …

semaglutide
magnetic resonance spectroscopy
proton magnetic resonance spectroscopy
fibroscan
blood test
  • 341 views
  • 07 Oct, 2022
  • 1 location
Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study

This phase II trial investigates how well lisinopril may work in preventing the progression of non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition where there is an accumulation of fatty cells in the liver. NAFLD increases a person's risk of developing liver cancer. Liver fibrosis is the common finding …

cancer
neutrophil count
  • 0 views
  • 07 Oct, 2022
  • 3 locations
The Liver Health Study for Patients With NAFLD

The study will investigate whether the level of fat stored in the liver is related to the liver's ability to burn fat.

diabetes
bariatric surgery
nutrition education
burn fat
fasting
  • 71 views
  • 25 Feb, 2022
  • 1 location
12-Month Once-a-week HIIT Improves Body Adiposity and Liver Fat

Obesity and non-alcoholic fatty liver disease (NAFLD) are two related growing epidemics that are becoming pressing public health concerns. High-intensity interval training (HIIT) is a promising cost-effective and time-efficient exercise modality for managing obesity and NAFLD. However, patients with obesity and NAFLD are generally inactive and unfit, and might feel …

diabetes
fats
liver disease
fatty liver
  • 10 views
  • 14 Jul, 2022
  • 1 location