Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 603 clinical trials
Balloon vs. Self Expanding Transcatheter Valve for Degenerated Bioprosthesis (BASELINE)

Transcatheter aortic valve implantation (TAVI) serves a growing spectrum of patients with symptomatic severe aortic stenosis (AS). Approximately 80% of surgical aortic valve replacements is performed using a bioprosthesis1. Durability of surgical bioprostheses varies based on the patient's age at the moment of implantation, type and size etc2. TAVI has …

tavi
transcatheter aortic valve implantation
stenosis
aortic valve replacement
regurgitation
  • 1 views
  • 04 Oct, 2022
  • 4 locations
California Fatherhood: Family-Focused, Interconnected, Resilient, and Essential (Cal-FIRE)

The Cal-FIRE project is designed to offer the R3 Academy for Dads, a robust 24-hour program, to predominantly low-income adult fathers, ages 18 and over in the state of California. The R3 Academy is an evidence-based parenting curriculum that helps fathers strengthen their relationships with their child, with their spouse/co-parent, …

Accepts healthy volunteers
  • 0 views
  • 21 Oct, 2022
A Double-Blind, Randomized, Placebo-Controlled Phase 2 Clinical Trial To Evaluate Safety And Efficacy Of KT-301 (Formerly US-APR2020) In Subjects With Chronic Kidney Disease Stage IV (CKD)

The aim of this Phase 2 study is to evaluate the safety and efficacy of the live biotherapeutic product, KT-301 (formerly US-APR2020), in the management of patients with CKD Stage IV.

  • 11 views
  • 22 Oct, 2022
  • 5 locations
Ad26.COV2.S as a Heterologous Booster in Adults After Single- or Two-Dose of Inactivated COVID-19 Vaccine

This study aims to address evidence gaps regarding the safety, reactogenicity and immune responses of a heterologous boost of a single dose of Ad26.COV2.S (half or full dose) at pre-specified time intervals in recipients who are documented to have received either 1-dose or 2-doses (primary series completion) of inactivated COVID-19 …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Impact of Surgical Timing on the Neurodevelopmental Prognosis of Newborns With Complex Congenital Heart Disease (CINC)

We propose a prospective observational study whose main objective will be to determine whether there is an association between age at surgery (days of life) and neurodevelopmental outcome in patients with CCHD. Secondly, we will study the relationship between age at surgery and (i) the incidence of WMI observed on …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy and Safety of NNC6019-0001 at Two Dose Levels in Participants With Transthyretin Amyloid Cardiomyopathy (ATTR CM)

This study is testing a potential new medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis.The study will look at if this medicine can reduce the symptoms of a

  • 0 views
  • 23 Oct, 2022
  • 1 location
Exploring the Relationship Between Advanced Multimodal Brain MRI Phenotypes, Genes and Cognitive Outcome in Adults With CHD

The main purpose of this proposal is to perform novel MRI analyses to determine the brain organizational changes associated with altered executive function and the modulating role of variants in neuroresilience and hypoxia response genes in adults with d-transposition of the great arteries (d-TGA).

Accepts healthy volunteers
  • 0 views
  • 16 Oct, 2022
  • 1 location
Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT (T4G RCT)

This is a Phase III randomized controlled trial of a passive ROM exercise program that will be performed in infants with HLHS and other single right ventricle anomalies following the Norwood procedure at PHN and Auxiliary Centers.

  • 20 views
  • 04 Oct, 2022
  • 4 locations
Autus Size-Adjustable Valve for Surgical Pulmonary Valve Replacement Early Feasibility Study

Prospective, single-arm, multi-center study to evaluate safety and preliminary effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 2 to 10 years inclusive (± 6 months) requiring surgical pulmonary valve replacement. The Autus Valve may be expanded pre-implant to match the subject's body size. Subjects will be evaluated prior …

  • 0 views
  • 10 Oct, 2022
  • 2 locations
Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial) (COMPASS)

COMPASS is a prospective multicenter randomized interventional trial. Participants with ductal-dependent pulmonary blood flow will be randomized to receive either a systemic-to-pulmonary artery shunt or ductal artery stent. Block randomization will be performed by center and by single vs. two ventricle status. Participants will be followed through the first year …

  • 0 views
  • 04 Oct, 2022