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Liver Disease Clinical Trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (1355) clinical trials

The Relationship of Initial Liver Profile and Outcome After Transplantation

Study population Tissue from all deceased adult liver transplant grafts will be collected. The test samples will be selected from procedures were the liver transplant recipient has developed IC. The control samples will include tissues from procedures were the transplant recipient had an uncomplicated outcome. There will be matching of ...

Phase N/A

TATE Versus TACE in Intermediate Stage HCC

Trans-arterial chemoembolization (TACE) is a standard care of intermediate stage Hepatocellular carcinoma (HCC) for 40 years without much improvement in efficacy. The key reason for lack of progress is that chemotherapy agents are not effective in hypoxia and cancer stem cells are induced under hypoxia. Tirapazamine, a hypoxia activated agent, ...

Phase

Glycemic Control and Surgical Site Infection Incidence Among Liver Transplantation Recipients

The Surgical Site Infections (SSI's) are the most frequent healthcare-associated infections and are an important infectious complication in the postoperative period among liver transplantation (LT) recipients. SSI incidence among LT recipients, whose allografts were from deceased donors, varied from 9.6% to 35.5% according to a recent literature review. In general ...

Phase N/A

Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study

To date, CEUS criteria for non-invasive diagnosis of HCC include arterial phase hyperenhancement, followed by contrast washout in the portal venous or late phase. We would like to investigate the following points: whether arterial hyperenhancement alone is sufficient for the definite diagnosis of HCC in cirrhosis with CEUS whether a ...

Phase N/A

Recombinant Human Arginase 1 (rhArg1) in Patients With Advanced Arginine Auxotrophic Solid Tumors

This is a phase 1, multiple sites, open label and non-randomized study to evaluate the safety of PEG-BCT-100. Patient enrollment and sample size will follow a classical 3 + 3 dose-escalation design. The study will enroll a maximum of 36 patients. Cohorts of 3 patients will receive an initial single ...

Phase

Prevalence of Sarcopenia and Undernutrition in Patients With Cirrhosis and Abdominal Hernia

Sarcopenia is a common condition in patients with cirrhosis, with a prevalence of around 50%. It is unknown if the presence of sarcopenia may influence the prevalence of abdominal hernias in this group of patients. Clinical, nutritional and radiological evaluation will be performed in two groups of cirrhotic patients to ...

Phase N/A

Quantifying Steatosis in Liver Transplant Donors

Living donor liver transplantation (LDLT) has been increasing worldwide due to the critical shortage of cadaveric donors and the rising number of patients awaiting liver transplantation. The long-term survival rates of LDLT are now comparable to that of deceased donor liver transplantation. Currently, two-thirds of all liver transplants performed in ...

Phase N/A

RadioEmbolization for the ADvancement of Y90 Glass Microspheres Registry

This study is a non-interventional, observational, prospective and global patient data registry. Approximately 1000 patients with liver cancers who are treated with TheraSpherewill be enrolled. Data regarding patient and treatment characteristics (TheraSphere and other anti-cancer treatments) will be collected within a 12 month period post TheraSphere administration to: Assess treatment ...

Phase N/A

A Study of Epacadostat an IDO1 Inhibitor in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

The purpose of this study is to test any good and bad effects of the combination therapy of epacadostat and pembrolizumab and to determine how well the combination therapy works in the treatment of patients with sarcoma.

Phase

13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF

The importance of identifying the patient with with ALI or ALF who is likely to die without a liver transplant cannot be overstated and has remained a primary focus of clinical investigation for 25 years. A recent analysis also conducted by the Acute Liver Failure Study Group (ALFSG) found that ...

Phase