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Liver Disease Clinical Trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (7) clinical trials

A Multi-Center Trial to Study Acute Liver Failure in Adults

Although ALF is truly an orphan disease affecting only about 2,000 persons per year, its severity, its frequency among young adults, and its high resource utilization justifies the attention paid to it. In addition, ALF has captured the interest and attention of researchers because of its unique pathogenesis and extreme ...

Phase N/A

Liver X Receptor (LXR) as a Novel Therapeutic Target in Diabetic Retinopathy (DR)

Diabetic retinopathy (DR) is a disabling microvascular complication. Despite recent advances using pharmacotherapy, a cure for DR has yet to be realized. Thus, a conceptual and technical breakthrough to identify novel targets, and a strategy to cure this complication is paramount. We believe that the recent clinical evidence from large ...

Phase N/A

Nottingham Community Liver Biomarkers Cohort

Objectives To establish a community based cohort with risk factors for liver disease and stratification for liver disease severity using non-invasive biomarkers. To establish the incidence of liver and cardiovascular morbidity and mortality in a community cohort. To explore the quantitative and qualitative indicators to potential alterations in patient lifestyle ...

Phase N/A

Immune Cell Dysfunction in Severe Alcoholic Hepatitis

Through bio-sampling this study investigates the relationship between the frequency and function of the cells of a patients immune system and how these change and impact on the outcome of alcoholic hepatitis. The investigators will examine the role of different cells of the immune system and how they may determine ...

Phase N/A

Liver Fibrosis in Sickle Cell Disease

Liver biopsy is the gold standard to examine the liver for iron deposits and histology. However, liver biopsy is invasive and involves a risk of bleeding and pain. Biopsy may also miss significant pathology if the small biopsy specimen is taken from an uninvolved part of the liver. Non-invasive techniques ...

Phase N/A

Identification of New Serum Diagnostic Markers of Hepatocellular Carcinoma

Liver cancer is a deadly cancer that is typically hard to diagnose and treat. The currently used blood marker for the clinical diagnosis of liver cancer is alpha-feto protein (AFP), which misses 40-60% of patients with liver cancer because it lacks sufficient specificity and sensitivity. The purpose of this study ...

Phase N/A

Genetic and Telomere Characteristics of High of Grade Soft Tissue Sarcomas

Aims The investigators plan a 2 year pilot observational study to: Identify and quantify circulating cell-fee DNA (cfDNA) in cases of Soft Tissue Sarcoma (STS) Investigate Telomere Maintenance Mechanisms (TMM) in STSs. Use TMM associated genetic mutations to identify and quantify tumour-derived cfDNA in STSs at time of tumour resection ...

Phase N/A