Urologic Cancer Clinical Trials

A listing of Urologic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 490 clinical trials
Nivolumab Plus Chemoradiotherapy in Patients With Muscle-invasive Bladder Cancer (MIBC) Not Undergoing Cystectomy

The purpose of this study is to investigate the effect synchronous use of nivolumab in addition to chemoradiotherapy in patients withnon-metastatic MIBC who are not candidates for radical cystectomy

carcinoma
invasive bladder cancer
nivolumab
bladder tumor
bladder carcinoma
  • 9 views
  • 13 Apr, 2022
  • 1 location
Complete Local Response to Neoadjuvant Chemotherapy in Patients With Muscle Invasive Bladder Cancer Evaluated by 15O-H2O PET/MR

Treatment of localized muscle invasive bladder cancer (MIBC) is radical cystectomy. Neoadjuvant chemotherapy (NAC) improves survival. Approximately 50-60% of all MIBC patients undergoing NAC before cystectomy are histopathological without remnant tumor in the cystectomy specimen (T0). However, there is currently no optimal method to evaluate whether the patient is true …

radical cystectomy
invasive bladder cancer
EGFR
cancer
bladder tumor
  • 0 views
  • 08 Aug, 2021
  • 1 location
Efficacy of Atezolizumab Concurrent With Radiotherapy in Patients With Muscle-invasive Bladder cáncer

Open, multicentre, phase II trial of atezolizumab with concurrent normofractionated radiotherapy in patients with localized muscle-invasive bladder cancer treated with a selective multimodality bladder conservative approach.

carcinoma
neutrophil count
invasive bladder cancer
bladder tumor
cancer
  • 10 views
  • 20 Feb, 2022
  • 10 locations
Bladder Tumor Biopsy Study to Improve Preoperative Determination of Stage and Grade

To assess whether the addition of a bladder tumor biopsy improves the level of agreement between the pretreatment endoscopic impression and the final postoperative pathology determination of stage and grade in non-muscle-invasive urothelial carcinoma of the bladder.

carcinoma
transitional cell carcinoma
bladder carcinoma
bladder tumor
  • 0 views
  • 24 Mar, 2022
  • 1 location
The Effectiveness and Safety of Neoadjuvant Intravesical Mitomycin-C Instillation

The aim of this study is to evaluate the effectiveness and safety of neoadjuvant intravesical mitomycin-C instillation in non-muscle invasive bladder cancer patients

invasive bladder cancer
mitomycin
cancer
bladder tumor
bladder cancer
  • 12 views
  • 23 Apr, 2022
  • 1 location
3 Tesla MRI in Patients With Bladder Cancer

RATIONALE: New diagnostic procedures, such as 3 Tesla magnetic resonance imaging (MRI), may help find bladder cancer and learn the extent of disease. PURPOSE: This clinical trial is studying how well 3 Tesla MRI works in finding cancer in patients with bladder cancer.

lymphadenectomy
cancer
bladder cancer
bladder tumor
radical cystectomy
  • 36 views
  • 02 May, 2022
  • 1 location
Intracorporeal vs Extracorporeal Urinary Diversion After Robot Assisted Radical Cystectomy

Intracorporeal urinary diversion (ICD) provides superior postoperative outcomes compared to extracorporeal urinary diversion (ECD). The investigators' hypothesis that ICD may provide clinical benefit is based on principles of less bowel and ureteral handling, superior operating room workflow, less exposure to the external environment, and optimal visualization with ICD while utilizing …

carcinoma
cancer
urinary diversion
ileal conduit
carcinoma in situ
  • 56 views
  • 23 Mar, 2022
  • 1 location
MOdified Urinary Conduit to Lower Strictures After radIcal Cystectomy

Cystectomy is the chosen treatment of bladder cancer in 400 cases every year in DK. In replacement of the removed bladder, a urinary diversion is constructed using 15cm of terminal ilium (Ad Modum Bricker). Ureteral strictures are diagnosed in 15% of the cystectomized patients, and these patients are at increased …

cancer
ileal conduit
bladder tumor
urinary diversion
bladder cancer
  • 0 views
  • 09 Jul, 2021
  • 5 locations
A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy

The purpose of this study is to test if immunotherapy with nivolumab alone or in combination with ipilimumab is safe and does not delay the planned bladder cancer surgery. The investigators want to see if treatment with these drugs prior to surgery may decrease the size of the bladder cancer …

carcinoma
neutrophil count
nivolumab
surgery for bladder cancer
bladder tumor
  • 9 views
  • 24 Mar, 2022
  • 7 locations
Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients

Bladder cancer is a common disease with high rates of mortality, especially at advanced stages. Neo-adjuvant cisplatin-based chemotherapy (NAC) followed by radical cystectomy is considered standard of care for patients with muscle invasive disease, as NAC improves surgical outcomes in these patients. However, some patients are ineligible for cisplatin-based chemotherapy …

invasive bladder cancer
bladder tumor
carboplatin
gemcitabine
radical cystectomy
  • 0 views
  • 29 May, 2022
  • 3 locations