Urologic Cancer Clinical Trials

A listing of Urologic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 507 clinical trials
Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)

Background Non-muscle-invasive bladder cancer is in the early stages. But it usually comes back after treatment. The drugs Vicineum and Durvalumab may help the immune system find and destroy cancer cells. Objective To test if the drugs Durvalumab and Vicineum together are safe and effective to treat people with bladder …

bcg vaccine
durvalumab
cancer
carcinoma
invasive bladder cancer
  • 257 views
  • 10 Aug, 2022
  • 1 location
Virtual Histology of the Bladder Wall for Bladder Cancer Staging

This is a phase Ib study of the safety and performance of a novel intravesical contrast-enhanced Magnetic Resonance Imaging protocol for determination of bladder cancer stage prior to transurethral resection of bladder tumor (21 subjects) or prior to radical cystectomy for muscle invasive disease (21 subjects). Subjects will undergo a …

transurethral bladder excision
cancer
intravesical administration
cystoscopy
radical cystectomy
  • 6 views
  • 21 Mar, 2022
  • 1 location
Investigation of Safety and Tolerability of Catumaxomab in Patients With NMIBC

The purpose of the study is to investigate the safety, tolerability, and preliminary efficacy of the monoclonal bispecific trifunctional antibody Catumaxomab in patients with non-muscle invasive bladder cancer (NMIBC).

intravesical administration
bladder tumor
carcinoma
invasive bladder cancer
neutrophil count
  • 1 views
  • 19 Apr, 2022
  • 1 location
Physical Rehabilitation Among Patients Undergoing Radical Cystectomy Due to Urinary Bladder Cancer (CanMoRe)

The main objective of the CanMoRe study is to evaluate the impact of a standardized and individually adapted exercise intervention in Primary Health Care aiming at improving physical function (primary outcome) and habitual physical activity, health related quality of life, fatigue and psychological well-being in patients undergoing radical cystectomy due …

bladder tumor
radical cystectomy
  • 0 views
  • 19 Apr, 2022
  • 1 location
MPDL3280A-treatment-IST-UMCG

To be able to evaluate the investigational imaging - 89Zr-MPDL3280A-PET, 89Zr-CD8 imaging and 18F-FB-IL2-PET - as complementary tools for selection of patients to be treated with MPDL3280A, within this treatment trial the investigators will assess safety, tolerability and anti-tumor activity of MPDL3280A in cancer patients, who have undergone investigational imaging.

epidermal growth factor
platelet count
mpdl3280a
EGFR
epidermal growth factor receptor
  • 6 views
  • 13 Mar, 2022
  • 1 location
Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients

Bladder cancer is a common disease with high rates of mortality, especially at advanced stages. Neo-adjuvant cisplatin-based chemotherapy (NAC) followed by radical cystectomy is considered standard of care for patients with muscle invasive disease, as NAC improves surgical outcomes in these patients. However, some patients are ineligible for cisplatin-based chemotherapy …

radical cystectomy
gemcitabine
carboplatin
bladder tumor
invasive bladder cancer
  • 0 views
  • 29 May, 2022
  • 3 locations
Paclitaxel-binding Albumin and Cisplatin as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer

This is a phase II study of Paclitaxel-binding albumin, Cisplatin as neoadjuvant chemotherapy in patients with muscle-invasive urothelial carcinoma of the bladder. Patients with muscle invasive urothelial carcinoma who are candidates for radical cystectomy will be enrolled.

  • 0 views
  • 23 Jan, 2021
  • 1 location
Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer (FB10)

Disease recurrence and progression is a major issue in high risk non-muscle-invasive bladder cancer (NMIBC). The current study compares two adjuvant instillation therapies in the treatment of high risk NMIBC. After resection of the tumour(s), patients will receive either traditional regimen of Bacillus Calmette-Gurin (BCG) instillations or combination treatment consisting …

carcinoma in situ
carcinoma
cancer
invasive bladder cancer
mitomycin
  • 18 views
  • 04 Feb, 2022
  • 7 locations
Predictive Impact of MMP2 and MMP9 Levels for Patients With Metastatic Kidney Cancer Treated With Anti-angiogenic Agents

Prospective research of Matrix Metalloproteinases (MMP) 2 and 9 as predictive biomarkers in metastatic kidney cancer patients treated with 2 anti angiogenic agents (Sunitinib or Pazopanib).

metastatic renal cell carcinoma
pazopanib
cancer
sunitinib
  • 7 views
  • 25 Feb, 2022
  • 1 location
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Background Gene transfer is a new cancer therapy takes white blood cells from a person and grows them in a lab. The cells are changed with a virus to attack tumor cells, then returned to the person. Researchers want to see if this therapy fights kidney cancer cells. Objective To …

treatment regimen
neutrophil count
carcinoma
platelet count
cancer
  • 73 views
  • 28 Jul, 2022
  • 1 location