Urologic Cancer Clinical Trials

A listing of Urologic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 138 clinical trials
Evaluating the Bacterial and Fungal Microbiome in Patients With Calcium Oxalate Urolithiasis and Renal Cell Carcinoma

The purpose of the study is to identify bacterial and fungal microbiome associated with calcium oxalate (CO) urolithiasis and renal cell carcinoma (RCC).

Accepts healthy volunteers
  • 0 views
  • 03 May, 2022
  • 1 location
Pembrolizumab With or Without Axitinib for Treatment of Locally Advanced or Metastatic Clear Cell Kidney Cancer in Patients Undergoing Surgery

This phase II trial studies how well pembrolizumab with or without standard of care axitinib works in treating patients with clear cell kidney cancer that has spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic) who are undergoing surgery. Pembrolizumab is an antibody …

direct bilirubin
axitinib
carcinoma
cancer
serum pregnancy test
  • 0 views
  • 12 May, 2022
  • 1 location
Lenvatinib and Everolimus in Renal Cell Carcinoma (RCC)

The purpose of this research study is to see what effect the combination of lenvatinib plus everolimus has in local and metastatic renal cell carcinoma to potentially make surgically unresectable tumors resectable.

cancer
serum pregnancy test
nephrectomy
vegf
angiogenesis
  • 0 views
  • 12 May, 2022
  • 1 location
A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma

CyberKnife Based Radiosurgery is a way to deliver large doses of radiation very accurately to a tumor. The ability of this technology to minimize radiation dose to organs adjacent to the target tumor allows a high dose to be delivered to the tumor, thus potentially increasing the efficacy of radiation …

ct scan
carcinoma
coagulopathy
cancer
brain metastasis
  • 40 views
  • 01 May, 2022
Renal Cell Carcinoma Microenvironment Discovery Project (REMEDY)

This study will obtain tumor samples from nephrectomy specimens in a multi-regional fashion and subject them to integrated genomics, pathological and radiological assessment. The goal is to better understand the the molecular basis for how various cells within the tumor microenvironment act in a coordinated manner to facilitate tumor progression …

nephrectomy
carcinoma
metastasis
  • 3 views
  • 06 May, 2022
  • 1 location
NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts

This study will explore the ability of patients on first line combination immunotherapy to sample cytokines at home. The data from this study will be used to evaluate the feasibility of in-home testing and the ability to analyse patients cytokine profiles retrospectively to help feed the development of further studies.

cancer chemotherapy
  • 0 views
  • 09 May, 2022
  • 1 location
Survey of Cabozantinib Used To Treat People With Renal Cell Carcinoma

This study is a survey in Japan of Cabozantinib tablets used to treat people with a type of kidney cancer called renal cell carcinoma. The study sponsor will not be involved in how the participants are treated but will provide instructions on how the clinics will record what happens during …

carcinoma
cancer
cabozantinib
kidney cancer
metastatic renal cell carcinoma
  • 0 views
  • 18 May, 2022
  • 1 location
A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma (COBALT-RCC)

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

carcinoma
karnofsky performance status
  • 43 views
  • 23 May, 2022
  • 7 locations
Neoadjuvant Study With Combination Immuno-oncology for Primary Clear Cell Renal Cell Cancer (NESCIO)

The NESCIO-trial is a multicenter, randomized, open-label, three-arm phase II trial investigating different combinations of neoadjuvant immunotherapy in patients with primary, resectable, intermediate to high-risk, clear-cell renal cell carcinoma. In this trial patients will be randomized 1:1:1 to receive either 2 cycles of nivolumab 360mg every 3 weeks (arm A), …

ipilimumab
carcinoma
cancer
nephrectomy
programmed cell death 1 ligand 1
  • 0 views
  • 24 May, 2022
  • 1 location
A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma (SPARC-1)

Primary Objective: To confirm the safety and feasibility of canakinumab and spartalizumab (PDR-001) administered using a standard dose / schedule in the neo-adjuvant setting in renal cell carcinoma Secondary Objectives: To assess the immune response to combination canakinumab and spartalizumab To assess anti-tumor activity as measured by pathologic downstaging

clear cell renal cell carcinoma
nephrectomy
neutrophil count
carcinoma
  • 1 views
  • 25 May, 2022