Urologic Cancer Clinical Trials

A listing of Urologic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 36 clinical trials
Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue

Background Prostate cancer is the most common noncutaneous cancer among men in the U.S. Researchers want to study blood, tissue, and fluid samples of people with prostate cancer. This will help them understand any changes in cells and genes. These changes might lead to the development and progression of prostate …

digital rectal examination
digital rectal exam
  • 6 views
  • 08 Aug, 2022
  • 1 location
SPECT/CT for the Characterization of Renal Masses

This trial studies how well technetium Tc-99m sestamibi single-photon emission computed tomography/computed tomography (SPECT/CT) works on clinical decision making in patients with kidney tumors. Diagnostic procedures, such as technetium Tc-99m sestamibi SPECT/CT may be a less invasive way to check for kidney tumors.

cancer
renal neoplasm
spect/ct
metastasis
ct scan
  • 1 views
  • 08 Aug, 2022
  • 1 location
Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)

Substudy 03A is part of a larger research study that is testing experimental treatments for renal cell carcinoma (RCC). The larger study is the umbrella study (U03). The goal of substudy 03A is to evaluate the safety and efficacy of experimental combinations of investigational agents in participants with advanced first …

lenvatinib
major surgery
carcinoma
systemic therapy
pembrolizumab
  • 0 views
  • 10 Aug, 2022
  • 33 locations
Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B)

Substudy 03B is part of a larger research study that is testing experimental treatments for renal cell carcinoma (RCC). The larger study is the umbrella study (U03). The goal of substudy 03B is to evaluate the safety and efficacy of experimental combinations of investigational agents in participants with advanced second …

major surgery
vegf
pembrolizumab
monoclonal antibodies
lenvatinib
  • 4 views
  • 10 Aug, 2022
  • 35 locations
A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011)

This study will compare the efficacy and safety of belzutifan + lenvatinib versus cabozantinib in participants with advanced renal cell carcinoma (RCC) with clear cell component after prior therapy. The primary hypothesis is that belzutifan + lenvatinib is superior to cabozantinib in terms of progression-free survival or overall survival.

measurable disease
advanced renal cell carcinoma
programmed cell death 1 ligand 1
lenvatinib
carcinoma
  • 0 views
  • 09 Aug, 2022
  • 128 locations
A Study of Belzutifan (MK-6482) as Monotherapy and in Combination With Lenvatinib (E7080/MK-7902) With or Without Pembrolizumab (MK-3475) in China Participants With Advanced Renal Cell Carcinoma (MK-6482-010)

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic profiles, and preliminary efficacy of belzutifan as monotherapy followed by belzutifan+lenvatinib combination therapy, as well as belzutifan combined with lenvatinib and pembrolizumab in China participants with advanced renal cell carcinoma.

major surgery
advanced renal cell carcinoma
measurable disease
pembrolizumab
lenvatinib
  • 0 views
  • 10 Aug, 2022
  • 5 locations
89Zr-DFO-Atezolizumab ImmunoPET/CT in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma

This is an exploratory clinical trial to assess the potential of 89Zr-DFO-Atezolizumab Positron Emission Tomography/Computed Tomography (PET/CT) scans in patients with locally advanced or metastatic renal cell carcinoma (RCC). This open label, nontherapeutic trial will test the correlation of 89Zr-DFO-Atezolizumab immunoPET/CT with programmed death-ligand 1 (PD-L1) expression and the response …

immune checkpoint inhibitor
pet scan
programmed cell death 1 ligand 1
ct scan
pd-l1
  • 0 views
  • 09 Aug, 2022
  • 1 location
Cabozantinib In Combo With NIVO + IPI In Advanced NCCRCC

This research study will assess whether cabozantinib, nivolumab and ipilimumab in combination are safe and effective in slowing down the growth of kidney cancer(renal cell carcinoma or RCC) that has advanced or spread to other areas the body.

measurable disease
ipilimumab
cancer
carcinoma
cabozantinib
  • 0 views
  • 09 Aug, 2022
  • 3 locations
Fecal Microbiota Transplantation to Improve Efficacy of Immune Checkpoint Inhibitors in Renal Cell Carcinoma (TACITO)

Renal cell carcinoma (RCC) is the sixth most common cancer in men and the eighth in women in the USA. In Italy RCC incidence was 11500 new cases in 2017, while mortality was 3371 cases in 2015. Increasing evidence suggests that response to immune checkpoint inhibitors (ICIs), a novel treatment …

cancer
carcinoma
  • 0 views
  • 11 Aug, 2022
  • 1 location
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

tremelimumab
ipilimumab
programmed cell death 1 ligand 1
il-2
pembrolizumab
  • 319 views
  • 12 Aug, 2022
  • 348 locations