Urologic Cancer Clinical Trials

A listing of Urologic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 135 clinical trials
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Background Gene transfer is a new cancer therapy takes white blood cells from a person and grows them in a lab. The cells are changed with a virus to attack tumor cells, then returned to the person. Researchers want to see if this therapy fights kidney cancer cells. Objective To …

treatment regimen
clear cell renal cell carcinoma
white blood cell count
measurable disease
hla-a
  • 73 views
  • 28 Jul, 2022
  • 1 location
Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy (BladderSpar)

Patients older than ≥18 years, with muscle-invasive bladder cancer unfit for radical cystectomy because of age, comorbidities, and/or patient's refusal. This study is designed as a multicentre, single-arm phase II study.

radical cystectomy
metastasis
white blood cell count
transurethral bladder excision
transurethral resection
  • 0 views
  • 28 Jul, 2022
  • 12 locations
Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer

This is a randomized, open-label, window of opportunity platform study in patients with muscle-invasive bladder cancer (MIBC) deemed ineligible to receive cisplatin-based neoadjuvant chemotherapy, who are scheduled to undergo definitive surgery (radical cystectomy). The primary objective of this study is to assess changes to immunogenomic markers after treatment with pembrolizumab …

radical cystectomy
transurethral resection
invasive bladder cancer
combinations
cancer
  • 12 views
  • 28 Jul, 2022
  • 2 locations
(CLONEVO): Cell cycLe inhbitiON to Target the EVolution of UrOthelial Cancer (CLONEVO)

Single-arm, open-label window-of-opportunity trial of neoadjuvant Abemaciclib in 20 patients, with tumor tissue obtained as standard of care at tumor resection (pre-Abemaciclib) and cystectomy (post-Abemaciclib)

radical cystectomy
carcinoma
transitional cell carcinoma
neutrophil count
white blood cell count
  • 17 views
  • 09 Aug, 2022
  • 2 locations
Bipolar Versus Mono-polar Needlescopic En Bloc TUR-BT

Non-muscle invasive bladder cancers (NMIBC) compose about 80% of bladder tumors. the stranded treatment of these tumors is TURBT. en bloc resection of NMIBC yields better mascularis propria with better oncological outcomes

bladder tumor
  • 0 views
  • 26 Jul, 2022
  • 1 location
Stereotactic Body Radiation Therapy in Treating Patients With Oligometastatic Renal Cell Carcinoma

This trial studies how well stereotactic body radiation therapy works in treating patients with kidney cancer that has spread to other places in the body. Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells …

liver metastases
metastasis
cancer
tumor cells
liver metastasis
  • 1 views
  • 27 Jul, 2022
  • 1 location
STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery (STRONG-CS)

treatment as usual (TAU) in ptt undergoing urological cancer surgery on surgical risk reduction.

  • 0 views
  • 01 May, 2022
The Personal Patient Profile Decision Support for Patients With Bladder Cancer (P3BC)

There is a pressing need to develop a personalized, value-based decisional tool for bladder cancer patients undergoing radical cystectomy (bladder removal) and urinary diversion to help them with communication with the physicians, shared decision making, and preparation for disease-management and follow-up care. The proposed intervention, the Personal Patient Profile - …

radical cystectomy
bladder tumor
urinary diversion
  • 0 views
  • 08 Aug, 2022
  • 1 location
CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition (Cyto-KIK)

The purpose of this study is to determine if the use of immunotherapy nivolumab and the targeted therapy cabozantinib prior to removal of the kidney, will increase the number subjects who are without any visible kidney cancer in their body at some point during the course of treatment.

serum pregnancy test
nivolumab
heparin
cancer
pet scan
  • 42 views
  • 22 Apr, 2022
  • 2 locations
Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL)

tract cancer who are not able to receive cisplatin therapy. Immunotherapy with monoclonal antibodies, such as avelumab, may help the body's immune system attack the cancer, and may interfere with the

  • 0 views
  • 24 Jul, 2022
  • 66 locations