Urologic Cancer Clinical Trials

A listing of Urologic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 140 clinical trials
Vaccine Response With NT-I7

Background People with cancer, and especially older people, have a weakened immune system (the defense system of the body). This is often caused by the treatments for cancer. Older cancer survivors are therefore more prone to getting infections, some of which are preventable through vaccines. But because their immune systems …

bladder tumor
erbb2
carcinoma
neutrophil count
her2/neu-positive breast cancer
  • 0 views
  • 29 Jul, 2022
  • 1 location
Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors

Nivolumab (and other agents affecting the anti-programmed death-1 [anti-PD-1] pathway) have demonstrated anti-tumor activity in multiple tumor types including non-small cell lung cancer (NSCLC), melanoma (MEL), renal cell carcinoma (RCC), and other cancers. However, there remains a large proportion of participants who do not achieve durable clinical benefit to nivolumab …

metastasis
nivolumab
gilbert's syndrome
direct bilirubin
carcinoma
  • 0 views
  • 01 May, 2022
  • 1 location
Project: Every Child for Younger Patients With Cancer

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

cytology specimen collection procedure
langerhans cell histiocytosis
carcinoma
metastatic disease
desmoid tumors
  • 366 views
  • 23 Jul, 2022
  • 126 locations
DNX-2440 for Resectable Colorectal Liver Metastasis

The purpose of this study is to test an experimental oncolytic adenovirus called DNX-2440 in patients with resectable multifocal (≥ 2 lesions) liver metastasis, who are scheduled to have curative-intent liver resection surgery. Up to 18 patients will receive two sequential intra-tumoral injections of DNX-2440 into a metastatic liver tumor …

metastasis
targeted therapy
carcinoma
gastrointestinal stromal tumor
squamous cell carcinoma
  • 0 views
  • 19 Apr, 2022
  • 1 location
A Study of HFB200301 in Adult Patients With Advanced Solid Tumors

The purpose of this study is to test the safety and tolerability of HFB200301 in patients with advanced cancers. There are two parts in this study. During the escalation part, groups of participants will receive increasing doses until a safe and tolerable dose of HFB200301 is determined. During the expansion …

braf v600e mutation
systemic therapy
carcinoma
lung carcinoma
BRAF
  • 0 views
  • 19 Apr, 2022
  • 2 locations
Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

The is a phase II, single arm, open-label, multi-site trial studying the combination of cryoablation therapy and dual checkpoint inhibition with nivolumab (anti-PD-1) and ipilimumab (anti-CTLA-4) given at the recommended phase 2 dose (RP2D) in pediatric and young adult patients with relapsed or refractory solid tumors.

interleukin
cancer treatment
growth factor
cytokines
tumor cells
  • 0 views
  • 19 Apr, 2022
  • 1 location
Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors (ASCR)

The purpose of this research study is to determine whether taking either of two low dose drugs that would prevent new blood vessels from growing after stem cell transplant is feasible, and what the side effects of taking each of these drugs after autologous transplant might be. The reason the …

edema
lymphoma
thalidomide
wilms' tumor
schwartz
  • 77 views
  • 30 Apr, 2022
  • 1 location
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

solid tumour
viral therapy
biological factors
tumors in children
cytokines
  • 484 views
  • 13 May, 2022
  • 1 location
Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery

This research trial studies how well biospecimen collection works in identifying genetic changes in patients with breast, prostate, colorectal, liver, or kidney cancer or multiple myeloma undergoing surgery. Studying samples collected during surgery may add to the understanding of cancer by looking for the genetic changes that cause early cancer …

biomarker analysis
cancer
systemic therapy
kidney cancer
carcinoma
  • 0 views
  • 10 Jul, 2022
  • 1 location
Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Background In a new cancer therapy, researchers take a person s blood, select a certain white blood cell to grow in the lab, and then change the genes of these cells using a virus. The cells are then given back to the person. This is called gene transfer. For this …

immunohistochemistry
antibiotics
cancer treatment
hepatitis b antigen
aldesleukin
  • 70 views
  • 25 Jul, 2022
  • 1 location