Urologic Cancer Clinical Trials

A listing of Urologic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 62 clinical trials
A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Gu rin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)

The purpose of this study is to evaluate recurrence-free survival (RFS) in participants treated with erdafitinib vs Investigator's Choice, for participants with high-risk non-muscle-invasive bladder cancer (NMIBC) who harbor fibroblast growth factor receptor (FGFR) mutations or fusions, and who recurred after bacillus calmette-guerin (BCG) therapy.

bladder cancer
invasive bladder cancer
intravesical chemotherapy
bladder tumor
mitomycin
  • 0 views
  • 21 Jun, 2021
  • 194 locations
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

This study is designed to assess the antitumor efficacy and safety of pembrolizumab in combination with chemoradiotherapy (CRT) versus CRT alone in participants with muscle-invasive bladder cancer (MIBC). The primary hypothesis is that pembrolizumab + chemoradiotherapy is superior to placebo + chemoradiotherapy with respect to bladder intact event-free survival.

invasive bladder cancer
bladder cancer
fluorouracil
bladder tumor
mitomycin
  • 76 views
  • 20 Jun, 2021
  • 105 locations
Stereotactic Magnetic Resonance Guided Radiation Therapy

This is a master prospective Phase I-II trial evaluating feasibility and efficacy of stereotactic magnetic resonance (MR) guided adaptive radiation therapy (SMART) in patients with cancer. The phase 1 study will evaluate the feasibility and safety of delivering SMART in patients with cancer. Phase 2 will evaluate efficacy of SMART …

primary cancer
stereotactic body radiation therapy
cancer
  • 0 views
  • 17 Jun, 2021
  • 1 location
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health

This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial, renal, and ovarian cancers. Overarching outcomes also include physical function and performance, muscle mass, quality of life, and health utilities.

ovarian cancer
body mass index
cancer chemotherapy
cancer
carcinoma in situ
  • 42 views
  • 16 Jun, 2021
  • 2 locations
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Solid Tumors Malignancies

This clinical trial is evaluating a drug called BT8009 alone and in combination with nivolumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The main goals of this study are to: Find the recommended dose of BT8009 …

EGFR
breast cancer
mammogram
nivolumab
line of therapy
  • 97 views
  • 13 Jun, 2021
  • 11 locations
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

bladder cancer
ovarian cancer
breast cancer
adenocarcinoma
cancer, ovarian
  • 179 views
  • 07 Jun, 2021
  • 12 locations
A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer

This trial will look at a drug called SEA-TGT (also known as SGN-TGT) to find out whether it is safe for patients with solid tumors and lymphomas. It will study SEA-TGT to find out what its side effects are. A side effect is anything the drug does besides treating cancer. …

combination chemotherapy
cyclophosphamide
doxorubicin
pembrolizumab
systemic therapy
  • 2 views
  • 16 Jun, 2021
  • 11 locations
Durvalumab and Vicinium in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)

Background Non-muscle-invasive bladder cancer is in the early stages. But it usually comes back after treatment. The drugs Vicinium and Durvalumab may help the immune system find and destroy cancer cells. Objective To test if the drugs Durvalumab and Vicinium together are safe and effective to treat people with bladder …

bladder cancer
invasive bladder cancer
bladder tumor
intravesical bcg
cancer
  • 255 views
  • 20 Jun, 2021
  • 1 location
Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC

This study assesses the effect of sequential radiation and durvalumab immunotherapy given as treatment prior to surgery with radical cystectomy for bladder cancer.

intravesical chemotherapy
bladder carcinoma
bladder tumor
hormone therapy
carcinoma
  • 0 views
  • 20 Jun, 2021
  • 4 locations
Celecoxib With Chemotherapy in Localized Muscle-Invasive Bladder Cancer

The purpose of this study is to compare patient tumor tissue before and after treatment with chemotherapy plus celecoxib. Investigators will look at gene expression, to see what effect celecoxib may have on tumor cells.

bladder cancer
invasive bladder cancer
bladder carcinoma
gilbert's syndrome
tumor cells
  • 10 views
  • 20 Jun, 2021
  • 2 locations