Bladder Carcinoma Clinical Trials

A listing of Bladder Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 256 clinical trials
Study of Combined VisioCyt Test and FGFR3 Mutations on a Urinary Sample to Diagnose Bladder Tumors (URODX-FGFR3)

This study is a case-control, propsective and muticentric clinical trial, which aim to compare the specificity and sensibility of VisioCyt urinary cytological test combined with FGFR3 mutation detection test to VisioCyt urinary cyological test on its own to detect bladder cancer. The case are patient in whom newly diagnosed, or …

FGFR3
bladder tumor
  • 0 views
  • 26 Apr, 2022
  • 1 location
Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery (MACS)

The current usage of antibiotic prophylaxis (AP) in radical cystectomy (RC) is aimed to reducing the incidence of surgical site infections and incidence of unnecessary prescribing of antibiotics. There are a huge number of different AP protocols according to Urological Associations. However, there is no convincing evidence to support variations …

radical cystectomy
carcinoma
bladder carcinoma
urinary diversion
  • 0 views
  • 16 Jun, 2022
  • 1 location
Effectiveness of an Immediate Postoperative Intravesical Instillation With Either Gemcitabine or Epirubicin in Patients With Urinary Bladder Cancer (Gemcitabine Epirubicin Normal SAline) (GENSA)

The natural history of non-muscle-invasive bladder cancer is characterised by recurrence and progression. We compare the effectiveness of gemcitabine hydrochloride and epirubicin hydrochloride, in combination with continuous saline irrigation, as an immediate single intravesical instillation in the potential reduction of the disease recurrence as well as progression.

gemcitabine
invasive bladder cancer
transurethral resection
bladder tumor
  • 0 views
  • 22 Mar, 2022
  • 1 location
DURvalumab in Combination With S-488210/S-488211 vAccine in Non-muscle Invasive Bladder CancEr (DURANCE)

DURANCE is a two part, phase Ib/II, multi-centre study to assess the safety and activity of S-488210/S-488211 in combination with durvalumab, in patients with non-muscle invasive bladder cancer (NMIBC).

durvalumab
carcinoma
neutrophil count
gilbert's syndrome
invasive bladder cancer
  • 0 views
  • 30 Apr, 2022
  • 1 location
Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC

Current treatment of localized muscle-invasive bladder cancer is still associated with high relapse and death rate as well as the need for complete bladder resection or irradiation. The primary objective of this trial is to increase the rate of pathologic complete remission (pCR) at the time of radical cystectomy by …

carcinoma
invasive bladder cancer
EGFR
bladder tumor
bladder instillation
  • 0 views
  • 04 Oct, 2022
  • 9 locations
PF-07225570 Alone or in Combination With an Anti-PD-1 Antibody in Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)

The primary objective of this study is to evaluate the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of PF-07225570 alone or in combination with an anti-PD-1 antibody in participants with recurrent non-muscle invasive bladder cancer. This study consists of 2 parts, single agent dose escalation (Part 1A), dose finding of …

carcinoma
radical cystectomy
invasive bladder cancer
bladder tumor
  • 0 views
  • 04 Oct, 2022
  • 2 locations
The Personal Patient Profile Decision Support for Patients With Bladder Cancer (P3BC)

There is a pressing need to develop a personalized, value-based decisional tool for bladder cancer patients undergoing radical cystectomy (bladder removal) and urinary diversion to help them with communication with the physicians, shared decision making, and preparation for disease-management and follow-up care. The proposed intervention, the Personal Patient Profile - …

radical cystectomy
urinary diversion
bladder tumor
  • 0 views
  • 04 Oct, 2022
  • 1 location
Hypofractionated IMRT With Concurrent Chemotherapy in Muscle-invasive Bladder Cancer (HIRACUM) (HIRACOM)

The purpose of this study is to investigate the side effects, quality of life, and treatment effects of concurrent chemo-hypofractionated intensity-modulated radiation therapy in bladder cancer. Twenty fractionation within 4 weeks are performed using hypofractionated intensity-modulated radiation therapy. As for the radiation dose, 2.8-3.2 Gy at a time, total dose …

invasive bladder cancer
transurethral resection
bladder tumor
carboplatin
metastasis
  • 0 views
  • 04 Oct, 2022
  • 1 location
Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs (radical cystectomy). Urinary tract infections are a common occurrence after robot-assisted radical cystectomy. Antibiotics such as trimethoprim-sulfamethoxazole …

trimethoprim-sulfamethoxazole
antibiotic therapy
sulfamethoxazole
invasive bladder cancer
antibiotics
  • 0 views
  • 10 May, 2022
  • 1 location
A Phase I Single-Arm Study of the Combination of Durvalumab (MEDI4736) and Vicineum (Oportuzumab Monatox, VB4-845) in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Gu(SqrRoot)(Copyright)Rin (BCG)

Background Non-muscle-invasive bladder cancer is in the early stages. But it usually comes back after treatment. The drugs Vicineum and Durvalumab may help the immune system find and destroy cancer cells. Objective To test if the drugs Durvalumab and Vicineum together are safe and effective to treat people with bladder …

durvalumab
carcinoma
cystoscopy
neutrophil count
invasive bladder cancer
  • 257 views
  • 17 Sep, 2022
  • 1 location