Bladder Carcinoma Clinical Trials

A listing of Bladder Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 261 clinical trials
Neoadjuvant Toripalimab in Combination With Gemcitabine and Cisplatin Therapy in Local Advanced Bladder Cancer Subjects

This is a pre-surgical study involving subjects with local advanced bladder cancer, who are candidates for neoadjuvant therapy. It is a single-arm phase II portion.

carcinoma
bladder tumor
measurable disease
gemcitabine
radical cystectomy
  • 0 views
  • 21 Mar, 2022
  • 1 location
Bladder Cancer and exeRcise Training During intraVesical thErapy (BRAVE)

Bladder cancer is the fifth most common cancer in Canada and has the eighth highest cancer mortality rate. The treatment for the most frequent type of bladder cancer is surgically removing the tumour followed by six weeks of medication placed within the bladder. There are physical and psychosocial challenges from …

bladder tumor
gemcitabine
mitomycin
invasive bladder cancer
  • 0 views
  • 24 Mar, 2022
  • 1 location
The Personal Patient Profile Decision Support for Patients With Bladder Cancer (P3BC)

There is a pressing need to develop a personalized, value-based decisional tool for bladder cancer patients undergoing radical cystectomy (bladder removal) and urinary diversion to help them with communication with the physicians, shared decision making, and preparation for disease-management and follow-up care. The proposed intervention, the Personal Patient Profile - …

bladder tumor
urinary diversion
radical cystectomy
  • 0 views
  • 08 Aug, 2022
  • 1 location
Effectiveness of an Immediate Postoperative Intravesical Instillation With Either Gemcitabine or Epirubicin in Patients With Urinary Bladder Cancer (Gemcitabine Epirubicin Normal SAline) (GENSA)

The natural history of non-muscle-invasive bladder cancer is characterised by recurrence and progression. We compare the effectiveness of gemcitabine hydrochloride and epirubicin hydrochloride, in combination with continuous saline irrigation, as an immediate single intravesical instillation in the potential reduction of the disease recurrence as well as progression.

bladder tumor
gemcitabine
invasive bladder cancer
transurethral resection
  • 0 views
  • 22 Mar, 2022
  • 1 location
Optimal Adjuvant Intravesical Therapy for Intermediate Risk Non Muscle Invasive Bladder Cancer: A Randomized Controlled Trial

The objective of this prospective, single-center randomized controlled trial is to identify the optimal adjuvant intravesical therapy in patients with intermediate risk (IR) non muscle invasive bladder cancer by comparing two commonly utilized intravesical regimens; intravesical immunotherapy (BCG) and intravesical chemotherapy.

bladder tumor
intravesical chemotherapy
intravesical bcg
invasive bladder cancer
  • 0 views
  • 23 Mar, 2022
  • 1 location
Effect of Fresh Gas Flow on Emergence Time

The purpose of this study is to evaluate the effect of fresh gas flow on emergence time in patients undergoing transurethral resection of bladder tumor.

bladder tumor
transurethral bladder excision
transurethral resection
  • 0 views
  • 05 Jun, 2022
  • 1 location
Care Planning Framework in Advanced Bladder Cancer (ABC123)

Pilot study assessing the feasibility and acceptability of the ABC123 framework, as well as goal concordance between patient and clinician stated goals. Patients >60 years old with recently diagnosed advanced, incurable bladder cancer making an initial treatment decision will be enrolled. The team will pilot test the ABC123 framework delivery …

bladder tumor
carcinoma
  • 0 views
  • 14 Jun, 2022
  • 1 location
Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC

Current treatment of localized muscle-invasive bladder cancer is still associated with high relapse and death rate as well as the need for complete bladder resection or irradiation. The primary objective of this trial is to increase the rate of pathologic complete remission (pCR) at the time of radical cystectomy by …

bladder instillation
carcinoma
EGFR
gemcitabine
intravesical bcg
  • 0 views
  • 13 Jul, 2022
  • 9 locations
Hypofractionated IMRT With Concurrent Chemotherapy in Muscle-invasive Bladder Cancer (HIRACUM) (HIRACOM)

The purpose of this study is to investigate the side effects, quality of life, and treatment effects of concurrent chemo-hypofractionated intensity-modulated radiation therapy in bladder cancer. Twenty fractionation within 4 weeks are performed using hypofractionated intensity-modulated radiation therapy. As for the radiation dose, 2.8-3.2 Gy at a time, total dose …

metastasis
carboplatin
transurethral resection
bladder tumor
invasive bladder cancer
  • 0 views
  • 24 Jul, 2022
  • 1 location
PF-07225570 Alone or in Combination With an Anti-PD-1 Antibody in Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)

The primary objective of this study is to evaluate the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of PF-07225570 alone or in combination with an anti-PD-1 antibody in participants with recurrent non-muscle invasive bladder cancer. This study consists of 2 parts, single agent dose escalation (Part 1A), dose finding of …

bladder tumor
radical cystectomy
carcinoma
invasive bladder cancer
  • 0 views
  • 13 Jul, 2022
  • 2 locations