Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1608 clinical trials
Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

The purpose of the study is to: Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated …

  • 2808 views
  • 21 Mar, 2021
  • 63 locations
Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors

The study proposes the use of Fludarabine, Busulfan, Anti Thymocyte Globulin Rabbit (ATG) and Total Body Irradiation as a preparative regimen before hematopoietic stem cell transplant from unrelated donor peripheral blood stem cells (PBSC). The hypothesis states that the 100 day mortality after this type of transplant will be significantly …

fludarabine
cancer
ejection fraction
total body irradiation
hypodiploidy
  • 10 views
  • 07 Nov, 2020
  • 1 location
Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)

The purpose of this study is to show superiority in complete responses of combination therapy MTC plus Glivec in patients with refractory or relapsed AML compared to a historical control which was treated with MTC alone.

refractory acute myeloid leukemia (aml)
secondary acute myeloid leukemia
serum bilirubin level
mitoxantrone
  • 15 views
  • 07 Nov, 2020
  • 1 location
AIDA2000 - Risk-Adapted Therapy for Patients With Acute Promyelocytic Leukemia

In AIDA 2000 therapy of acute promyelocytic leukemia (APL) is given in a risk-adapted manner. Risk factors are age and white-blood-cell (WBC)-count at diagnosis. Induction therapy is done

methotrexate
retinoids
consolidation therapy
mitoxantrone
tretinoin
  • 40 views
  • 07 Nov, 2020
  • 1 location
High-Dose Methotrexate (MTX) for Adult Acute Lymphoblastic Leukemia (ALL)

The purpose of this study is to investigate the clinical efficacy of high-dose methotrexate consolidation therapy for adult patients with BCR-ABL-negative ALL.

methotrexate
cyclophosphamide
mercaptopurine
doxorubicin
daunorubicin
  • 12 views
  • 07 Nov, 2020
  • 1 location
Therapy Optimisation for the Treatment of Hairy Cell Leukemia

The trial will test the effectiveness and toxicity of subcutaneous treatment with one cycle of cladribine in patients with hairy cell leukemia requiring treatment. They have to be

  • 22 views
  • 08 May, 2021
  • 74 locations
Dexamethasone in Refractory or First Relapsed Acute Myeloid Leukemia

regrowth and relapse. Moreover, it has been experimentally shown that leukemic cells in acute myeloid leukemia patients who relapse become sensitive to glucocorticoids treatment highlighting a novel

  • 0 views
  • 25 Jan, 2021
  • 5 locations
The WWRD Study: AVM0703 for Treatment of Leukemia or Lymphoma

This is an open-label, Phase 1/2 study designed to characterize the safety, tolerability, Pharmacokinetics(PK), and preliminary antitumor activity of AVM0703 administered as a single intravenous (IV) infusion to patients with lymphoid malignancies.

  • 0 views
  • 17 Apr, 2021
  • 3 locations
Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

is not yet known whether gemtuzumab ozogamicin is more effective than standard supportive care in treating older patients who have acute myeloid leukemia. PURPOSE: This randomized phase II

myeloid leukemia
monoclonal antibodies
cancer
gemtuzumab ozogamicin
monoclonal antibody therapy
  • 30 views
  • 07 Nov, 2020
  • 2 locations
Multi-center Trial of Revlimid and Rituximab for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)

The study is a two-arm, multi-center trial of Revlimid® and Rituximab, for the frontline treatment of patients with Chronic Lymphocytic Leukemia (CLL) designed and conducted by the CLL

platelet count
neutrophil count
rituximab
lymphoid leukemia
cancer
  • 42 views
  • 07 Nov, 2020
  • 3 locations