Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 613 clinical trials
A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

The purpose of this research is to find the best dose of genetically modified T-cells, to study the safety of this treatment, and to see how well it works in treating patients with B cell non-Hodgkin lymphoma that has come back (relapsed) or did not respond to previous treatment (refractory).

leukapheresis
fludeoxyglucose
positron emission tomography
tositumomab
ct scan
  • 156 views
  • 04 Oct, 2022
  • 1 location
CD8 Depleted, Non-Engrafting, HLA Mismatched Unrelated Donor Lymphocyte Infusion in Patients With MDA and Secondary AML

or after progression of MDS to acute myeloid leukemia (AML). Funding source - FDA OOPD.

decitabine
leukemia
anemia
acute promyelocytic leukemia
acute leukemia
  • 0 views
  • 18 Oct, 2022
  • 1 location
Zein Nanoparticles for Glycemic Control (GLUCOCAPS)

The use of zein nanoparticles as vehicles for drug delivery is under study, but of the effects observed in empty nanoparticles, in laboratory animals, the reduction of glucose levels was something worth studying. Thus, the present research on patients with prediabetes has been proposed. The objective is to assess the …

Accepts healthy volunteers
  • 0 views
  • 24 Oct, 2022
Study of Lacutamab in Peripheral T-cell Lymphoma

-cell lymphoma with TFH phenotype), Anaplastic large cell lymphoma (ALCL), Adult T-cell leukemia/lymphoma (ATL), Hepatosplenic T-cell lymphoma (HSTL), Enteropathy-associated T-cell lymphoma (EATL

stem cell transplantation
brentuximab
ct scan
leukemia
angioimmunoblastic t-cell lymphoma
  • 0 views
  • 04 Oct, 2022
  • 38 locations
Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

This phase II trial studies how well nivolumab works for the treatment of hematological malignancies that have come back (relapsed), does not respond (refractory), or is detectable after CAR T cell therapy. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may …

monoclonal protein
ct scan
cell therapy
large b-cell lymphoma
lymphoid leukemia
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase IIIb Study of the Safety and Efficacy of Tisagenlecleucel Out of Specification for Commercial Release in Patients Who Are Consistent With the Label Indication

This study will evaluate the safety of tisagenlecleucel that is out of specification( OOS) for release as commercial product. Specifically, this study will evaluate the safety of CTL019 in the patients treated within the approved label by Japan Health Authority in Part 2. Only for Part 1, in addition to …

leukapheresis
lymphoma
b-cell lymphoma
leukemia
follicular lymphoma
  • 4 views
  • 24 Oct, 2022
  • 33 locations
Safety Study of SLC-391 in Subjects With Solid Tumors

activity against different tumour cell lines in vitro and efficacy in different animal models including nonsmall cell lung cancer (NSCLC), chronic myeloid leukemia (CML) and (acute myeloid leukemia (AML

endocrine therapy
mitomycin
lung cancer
targeted therapy
cancer
  • 15 views
  • 04 Oct, 2022
  • 3 locations
Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) Treatment

The primary objective of this study is to evaluate the safety of zanubrutinib (also known as BGB-3111) in chronic lymphocytic leukemia/small lymphocytic lymphoma, Waldenström macroglobulinemia

b-cell small lymphocytic lymphoma
blood transfusion
lymphoma
platelet count
chronic lymphocytic leukemia
  • 108 views
  • 07 Oct, 2022
  • 29 locations
A Phase I, Open-label, Multi-center Study of PIT565 in Patients With Relapsed and/or Refractory B-cell Malignancies

recommended doses (RDs), schedule and route of administration in relapsed and/or refractory B-cell Non-Hodgkin lymphoma (R/R B-NHL) and relapsed and/or refractory B-cell acute lymphoblastic leukemia (R/R B

lymphocytic leukemia
monoclonal antibodies
leukemia
cancer chemotherapy
  • 0 views
  • 27 Oct, 2022
  • 2 locations
A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Background In allogeneic stem cell transplantation (SCT), stem cells are taken from a donor and given to a recipient. Sometimes the recipient s immune system destroys the donor s cells. Or donor immune cells attack the recipient s tissues, called graft-versus-host disease (GVHD). This is less likely when the recipient …

blood transfusion
minimal residual disease
residual disease
ct scan
flow cytometry
  • 23 views
  • 21 Oct, 2022
  • 2 locations