Home » Clinical Trials »  Search Clinical Trials

Therapeutic Areas:  |  Neurology  |  Ophthalmology

Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters

Retina Clinical Trials

A listing of Retina medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (217) clinical trials

The Role of suPAR Biomarker in Blood Samples of Breast Cancer Patients During and Post Doxorubicin Chemotherapy: Causative vs. Predictor

Hypothesis 1: Higher suPAR at baseline will predispose to DOX-induced cardiomyopathy to be observed by histology in mouse models, and tested using LVEF (Left Ventricular Ejection Fraction) assessment, and surrogate cardiovascular outcome measures as described in humans. Hypothesis 2: suPAR is a marker of DOX-induced cardiomyopathy after exposure to DOX, ...

Phase N/A

Telescope Exchange Study

VisionCare's Implantable Miniature Telescope (IMT, intraocular telescope or telescope) is indicated for monocular implantation to improve vision in eyes of patients at least 65 years of age with severe to profound vision impairment caused by bilateral central scotomas associated with end-stage age-related macular degeneration (AMD). Patients with end-stage AMD who ...

Phase N/A

Early MRI Detection of Myocardial Deterioration as a Preventive Disease Staging and Prognostic Biomarker in Insulin Resistance

Cardiac fibrosis has been linked to adverse outcomes in non-ischemic cardiomyopathy. Fibrosis is also detectable in diabetic patients, but does not appear to closely track with insulin sensitivity. Hence, fibrosis may be an independent risk factor for adverse outcomes in IR and diabetic patients. As a result, a critical need ...

Phase N/A

Same Day Subcutaneous ICD And Send Home (DASH)

This is a prospective, nonrandomized, descriptive, single center study designed to assess the rate of successful completion of the study protocol in consecutive patients undergoing S-ICD implantation. Objectives To prospectively evaluate the same day discharge protocol for patients undergoing S-ICD implantation. Primary Endpoint 1. Rate of successful completion of S-ICD ...

Phase N/A

The Effects of Regular Eye-training With a Mobile Device on Adult Patients With AMD

In the presented study a training-therapy in patients with dry AMD war evaluated. The main focus was on remote visibility and thus better handling of daily activities. Therapy with high-contrast administration is used for amblyopia in childhood. Furthermore, simulation therapy is used in hemianopsia in the adult age, in which ...

Phase N/A

Fourier Transformed Infrared Spectroscopy in Macular Surgery

Purpose of the present study is to analyse components of ERM and ILM, giving hints for the origin of cells producing ERM. In contrast to electron microscopy, FTIR spectroscopy does not need any chemical fixation of the membranes and therefore structure of components of ERM and ILM are not changed ...

Phase N/A

Perifoveal Vascular Network Assessed by OCT-Angiography in Type I Diabetes Mellitus

Diabetic retinopathy (DR) is the leading cause of blindness in type 1 Diabetes Mellitus (DM) patients, as a consequence of impaired blood flow in the retina. Optical coherence tomography angiography (OCT-A) is a newly developed, non-invasive, retinal imaging technique that allows detection of perfused and non perfused areas of the ...

Phase N/A

Retina Microvascular Remodeling and Cognitive Function In Hypertension

Our project stands on physiopathological and cognitive angles, and is mainly based on the major role of large and small arteries elasticity on cognitive aging. It will benefit from the recent innovative accurate and non invasive techniques such as MRI for central large arteries and adaptative optics for retina arterioles ...

Phase N/A

Thermal Screening for Early Diabetic Peripheral Neuropathy (DPN)

This study focuses on further development and testing of a microvascular functional imaging system, a computer-based system for screening thermal video images, designed to detect biomarkers of diabetic peripheral neuropathy (DPN). Additionally, severity levels of diabetic retinopathy (DR) will be compared with those of DPN. All participants in this study ...

Phase N/A

SPT Screening in Irradiated Hereditary Retinoblastoma Survivors

Rationale: Hereditary retinoblastoma survivors have an increased risk to develop second primary tumors (SPT) at a later age (with the highest risk in their teens), especially when they have been irradiated for retinoblastoma. The investigators hypothesize that regular screening with magnetic resonance imaging (MRI) could lead to early detection of ...

Phase N/A