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Retina Clinical Trials

A listing of Retina medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (216) clinical trials

We are seeking participants for a new clinical research study to evaluate the long term treatment effects of an investigational medication on diabetic retinopathy progression in adults with type 2 diabetes.  

Phase N/A

Secondary Objectives All-cause mortality, VT or VF alone, risk of cardiac death, and sudden cardiac death for the total cohort, as well as by sex and by the implanted device type. Compare the predicted incidence of sudden death using the Seattle Proportional Risk score to the observed incidence in this ...

Phase N/A

Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease

OBJECTIVE Primary The purpose of this investigation is to evaluate the efficacy of the sympathectomy in the reduction of VT episodes in patients with Chagas cardiomyopathy. Secondary To compare the efficacy of sympathectomy with ablation of VT and with the optimal drug therapy. To evaluate the density of ventricular premature ...

Phase N/A

Adrenocorticotropic Hormone (ACTH) for Post-op Inflammation in Proliferative Vitreoretinopathy (PVR)

This is a pilot study to measure levels of albumin and inflammatory cytokines [including Transforming Growth Factor-Beta (TGF-) and Interleukin-1 Beta (IL-1)] in the aqueous humor of post-operative proliferative vitreoretinopathy patients receiving subcutaneous injections of H.P. Acthar, an adrenocorticotropic hormone (ACTH) analog. The study will be conducted at the Wilmer ...

Phase N/A

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Background Patients with the von Hippel-Lindau (VHL) familial cancer syndrome demonstrate manifestations in a variety of organs, including the pancreas. Pancreatic manifestations can range from benign cysts and micro cystic adenomas to neuroendocrine tumors of the pancreas which are capable of regional and distant metastases. These neuroendocrine tumors can result ...

Phase N/A

Advancing Understanding of Transportation Options

The investigators will use a multi-site, two-armed randomized controlled trial of older drivers (n=300; 70 years) from clinical settings, and one family member each (n=up to 300), with longitudinal follow-up. Study goals are to test how much the DDA improves outcomes and identify who benefits most from the DDA. Evaluation ...

Phase N/A

Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comt

Medical progress and modification of lifestyles have prolonged life expectancy, despite the development of chronic diseases. The support and care are often provided by a network of informal caregivers composed of family, friends, and neighbors. They became essential to help maintening the elderly persons to live at home. It has ...

Phase N/A

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

We propose to characterize the etiology and natural history of rare and uncommon diseases, both known and unknown that present with symptoms and signs associated with the risk of overt or potential cardiovascular dysfunction. We will also study rare genetic modifiers and identify novel disease mechanisms contributing to common cardiovascular ...

Phase N/A

AMD Ryan Initiative Study (ARIS)

Objective Late age-related macular degeneration (AMD) is the leading cause of blindness among elderly in the United States. At present, the current classification systems do not take into consideration advances in imaging technology, visual function biomarkers, as well as genotyping and phenotyping. Clinical sites in the United States and around ...

Phase N/A

Analyzing Retinal Microanatomy in ROP

Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that may impact vision in vulnerable preterm neonates for a lifetime. Clinical care of infants with ROP decreases the likelihood of blindness, but abnormal vision is common, especially in those with disease severe enough ...

Phase N/A