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Retina Clinical Trials

A listing of Retina medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (214) clinical trials

We are seeking participants for a new clinical research study to evaluate the long term treatment effects of an investigational medication on diabetic retinopathy progression in adults with type 2 diabetes.  

Phase N/A

Secondary Objectives All-cause mortality, VT or VF alone, risk of cardiac death, and sudden cardiac death for the total cohort, as well as by sex and by the implanted device type. Compare the predicted incidence of sudden death using the Seattle Proportional Risk score to the observed incidence in this ...

Phase N/A

AMD Ryan Initiative Study (ARIS)

Objective Late age-related macular degeneration (AMD) is the leading cause of blindness among elderly in the United States. At present, the current classification systems do not take into consideration advances in imaging technology, visual function biomarkers, as well as genotyping and phenotyping. Clinical sites in the United States and around ...

Phase N/A

Analyzing Retinal Microanatomy in ROP

Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that may impact vision in vulnerable preterm neonates for a lifetime. Clinical care of infants with ROP decreases the likelihood of blindness, but abnormal vision is common, especially in those with disease severe enough ...

Phase N/A

Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity With Evaluation of the ABCA4 Gene

OBJECTIVE The objective of this study is to investigate whether there is a correlation between genetic mutations, beginning with an analysis of ABCA4, and Plaquenil -induced retinal toxicity and to describe the phenotype of Plaquenil -induced retinal toxicity. STUDY POPULATION: The study will enroll 45 patients, 18 years of age ...

Phase N/A

Aflibercept Injection Into the Vitreous Body of the Eye: Study to Learn More About Patient Relevant Outcomes Real World Treatment Patterns and How Well the Treatment Works for Patients Suffering From Abnormal Growth of New Blood Vessels Under the Retina.

In this clinical study researchers want to gain a deeper understanding of treatment consistence under real world conditions over the course of 24 months of Aflibercept injections into the eye for patients suffering from abnormal growth of new blood vessels under the retina (neovascular age-related macular degeneration). The study aims ...

Phase N/A

Associations Between Retina and Brain Function

Case-control studies and meta-analysis have reported that several fundus features, especially the thickness of the peripapillary retinal nerve fiber layer, are related to the brain degeneration and cognitive impairment. In our study, we aim to quantitatively assess retina features using OCT and define its associations with brain development and intelligence ...

Phase N/A

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Background Patients with the von Hippel-Lindau (VHL) familial cancer syndrome demonstrate manifestations in a variety of organs, including the pancreas. Pancreatic manifestations can range from benign cysts and micro cystic adenomas to neuroendocrine tumors of the pancreas which are capable of regional and distant metastases. These neuroendocrine tumors can result ...

Phase N/A

Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies

Background -Laboratory-based investigations have contributed to an improved understanding of the biology of cancer and to the development of new therapies for pediatric malignancies. Objectives -Systematic Molecular, Genomic, Proteomic, Metabolomic ( Omic ) and other profiling for enrolled subjects. Eligibility Pediatric or Adult subjects of any age with one of ...

Phase N/A

Cell Collection to Study Eye Diseases

This study will establish a repository of biospecimens to generate induced pluripotent stem (iPS) cells, which will be used to determine molecular mechanisms for potentially blinding eye diseases including but not limited to: Best Vitelliform Dystrophy (Best Disease); Late-Onset Retinal Degeneration (L-ORD); Age-Related Macular Degeneration (AMD); Leber congenital amaurosis (LCA); ...

Phase N/A