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Retina Clinical Trials

A listing of Retina medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (268) clinical trials

A Study of a New Surgical Treatment of Macular Hole Retinal Detachment in High Myopia

This study uses a new surgical method (vitrectomy combined with inverted internal limiting membrane insertion and intraocular sterilized air tamponade) to assess its effectiveness and safety on the prognosis of macular hole retinal detachment secondary to high myopia, and also compares this new type of surgery with the current commonly ...

Phase N/A

Early Laser Treatment for Diabetic Eye Disease in China : A Pilot Randomized Trial

China now has the world's largest number of diabetic persons. Population studies show that only 10% of Chinese rural-dwellers with DR receive therapy. The current standard approach to treatment of DR often requires patients to return for multiple examinations over years, before they reach trial-proven criteria for treatment. This long ...

Phase N/A

Investigation of Vascular Pathology in Eye Diseases Using Using Optical Coherence Tomography Angiography (OCT-A)

Optical coherence tomography angiography (OCTA) is a new non-invasive imaging technique that employs motion contrast imaging to high-resolution volumetric blood flow information. OCTA compares the decorrelation signal between sequential OCT b-scans taken at precisely the same cross-section in order to construct a map of blood flow. At present, level 1 ...

Phase N/A

Analysis of Angiogenic Factor Levels in Eyes With Diabetic Retinopathy

This prospective, case-control study included 50 patients(50eyes) with severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy and 50 patient with nondiabetic retinopathy or cataract. Aqueous humor was taken before injection of anti-vascular endothelial growth factor agent or pars plana vitrectomy for other retinal disease. Angiogenic and non-angiogenic proteins were analyzed.

Phase N/A

Screening for Endolymphatic Sac Tumours (ELSTs) in Von Hippel-Lindau (vHL) Patients

Background von Hippel-Lindau disease (vHL) is a hereditary multi-system disease requiring life-long prophylactic surveillance. Affected individuals are predisposed to development of tumors and cysts in multiple organs. In recent years, it has become apparent that endolymphatic sac tumors (ELSTs), aggressive tumors of the petrous bone, occur in up to 16% ...

Phase N/A

Trial of Ocular Subretinal Injection of a Recombinant Adeno-Associated Virus (rAAV2-VMD2-hMERTK) Gene Vector to Patients With Retinal Disease Due to MERTK Mutations

A recombinant adeno-associated virus serotype 2 (rAAV2) vector has been altered to carry the human MERTK (hMERTK) gene. This vector has been shown to restore vision in animal models that resemble human MERTK-associated Retinitis Pigmentosa (RP), an incurable retinal degeneration that causes severe vision loss. The proposed study is an ...


Resveratrol for Exudative Age-Related Macular Degeneration

Interventional, prospective, randomized, comparative monocentric study aiming to evaluate the safety and efficacy of Resveratrol to reduce the progression of exudative Age-Related Macular Degeneration. Comparison of incidence of choroidal neaovascularization between each study group will be performed.

Phase N/A

Stem Cell Therapy for Outer Retinal Degenerations

To determine whether the surgical implantation of a human embryonic stem cell-derived retinal pigmented epithelium (hESC-RPE) monolayer seeded onto a polymeric versus hESC-RPE injections into the sub retinal space is a safe procedure. 6 Patients will receive hESC-RPE cell injections (100000 cells) in the sub retinal space (2 Dry Age-related ...


Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes

This study is designed to evaluate and compare in-tissue performance of OCT scans on the new Optos P200TE, versus the predicate Optos Spectral OCT/SLO device.

Phase N/A

Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.

The investigators include in the study all successive patients operated by the same surgeon. The study takes place in the S.N. Fyodorov "Eye Microsurgery" Federal State Institution located in Moscow, Russian Federation. Patients are randomized in two groups with stratified block randomization. Strata were defined by combination of two binary ...

Phase N/A