Retina Clinical Trials

A listing of Retina medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 405 clinical trials
Treat-and-extend Using Aflibercept for Type 3 Neovascularization

Type 3 neovascularization is a subtype of neovascular age-related macular degeneration (AMD) that is characterized by intraretinal neovascularization. Treat-and-extend (TAE) regimen is a widely-used, effective anti-vascular endothelial growth factor treatment regimen for neovascular AMD, regardless of subtypes of AMD. The purpose of the present study is to investigate the 18-month …

  • 04 Oct, 2022
  • 1 location
An Interventional, Confirmative, Post Marketing Clinical Followup (PMCF) Study to Evaluate Performance and Safety of Ophthalmic Solutions Used to Relieve Dry Eyes Like Symptoms in Glaucoma Patients. (M-GLAU-01-2020)

Study Rationale: The glaucomas are a group of optic neuropathies characterized by progressive degeneration of retinal ganglion cells. These are central nervous system neurons that have their

  • 03 Apr, 2023
  • 1 location
Randomized Trial Comparing Immediate Versus Deferred Surgery for Symptomatic Epiretinal Membranes (Protocol AM)

Vitrectomy to remove an epiretinal membrane (ERM) is one of the most common procedures performed by retinal surgeons. Patients who present with significant macular changes on optical coherence

  • 23 Oct, 2022
  • 24 locations
Subthreshold Laser Treatment in Intermediate Age-related Macular Degeneration With Nascent Geographic Atrophy Study (LIANA)

outcome is the change in retinal function of laser-treated study eyes compared to sham-treated study eyes over 12 months. Safety will be the proportion of laser-treated eyes that lose 10+ letters of

geographic atrophy
retinal pigment
corrected visual acuity
  • 11 Apr, 2023
  • 1 location
Combination of Ranibizumab and Targeted Laser Photocoagulation (CoRaLaII)

Intravitreal injections of Ranibizumab will be applied in all patients according to treatment guidelines. The experimental group will receive additional targeted laser photocoagulation of the peripheral areas of capillary non-perfusion (up to 4 laser treatments within 1st year of the study). Based on the long-term observation after CoRaLa I study …

  • 24 May, 2022
  • 11 locations
Time-restricted Eating to Improve Body Fat Mass in Overweight and Obese Individuals With Morning Chronotype: A Randomized, Open-label, Multi-arm Trial

central clock, retinal sensing of ambient light, and daily feeding-fasting cycles. The chronotype has an influence on behavioral patterns, where some people describe that they are more alert in the

  • 27 Oct, 2022
  • 1 location
Targeted Fluorescence Imaging in AMD (LEAF)

naïve wet AMD and wet AMD by observing the uptake in retinal, choroid and neovascular tissue. Nature and extent of the burden and risks associated with participation, benefit and group

  • 09 Apr, 2023
  • 1 location
A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU) (USTEKINISU)

posterior segment, either primarily in the vitreous (intermediate uveitis), the choroid or retina (posterior uveitis), or involving the entire eye (panuveitis). The term "uveitis" denotes a heterogeneous

  • 15 Feb, 2022
  • 3 locations
A Prospective International Multicenter Clinical Trial for Eyes With Relapsed Retinoblastoma

While 95% of patients with retinoblastoma can be cured nowadays, treatment of relapse remains challenging, ending often in enucleation and/or radiotherapy. In the last 10 years, new treatment modalities have been developed to give the chance of cure also in relapse, avoiding enucleation which results in esthetic sequelae and orbital …

recurrent retinoblastoma
  • 11 Dec, 2021
  • 1 location
Study to Evaluate the Efficacy and Safety of RZ402 in Diabetic Macular Edema (DME)

The objective of this trial is to assess the safety, efficacy, and tolerability of RZ402 in patients with Diabetic Macular Edema.

  • 09 Apr, 2023