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Eye Disease Clinical Trials

A listing of Eye Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (29) clinical trials

Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane Ultra and Ultra Preservative Free (087LATAMFIV)

Design Controlled, double-blind, randomized, clinical trial comparing the safety and efficacy parameters between a group of subjects with a diagnose of mild to moderate tear film dysfunction syndrome under a regimen of ophthalmic solution lubricant drops PRO-087 versus subject under Systane Ultra or Systane Ultra preservative free, with the same ...

Phase

A Study to Assess the Clinical Outcomes of Surgical Phaco Segmentation Techniques in Patients Undergoing Cataract Surgery

The purpose of this research study is to evaluate the clinical outcomes of different cataract surgical techniques for lens fragmentation in subjects undergoing routine cataract surgery.

Phase

Tear Lipid Layer Thickness With Emollient Eye Drops

This study will objectively evaluate two US Monograph lubricant eyedrop formulations (Allergan, plc). Refresh Optive ADVANCED will be compared to an investigational formula with additional compendial ingredients (Refresh Optive MEGA 3) in subjects with dry eye symptoms and lipid layer thickness < 65 nm at baseline in a randomized, cross-over ...

Phase

Effect of Slow-release Melatonin (Circadin ) Therapy on Idiopathic RBD: a Pilot Study

Investigators planned to administer low (2mg) and high (6mg) dose slow-release melatonin and the placebo for 4 weeks and evaluate Clinical Global Impression scale, RBD questionnaire, PSQI, Epworth sleepiness scale, and quality of life questionnaire (SF-36v2) before and after the treatment along with possible side effects and drug compliance.

Phase

Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia

The research deals with amblyopia or lazy eye, a condition that affects about 3% of the population, and results in a variety of visual deficits. Recent work suggests that there is limited neural plasticity in the visual system of adults with amblyopia. This study is aimed at understanding and increasing ...

Phase

Influence of Three Different Formulations of Lachrymal Substitutes on Tear Film Thickness and Other Signs and Symptoms in Patients With Moderate to Severe Dry Eye Syndrome

Dry eye syndrome is a highly prevalent ocular disease with an increasing incidence in the elderly population. Topically administered lubricants are the basis for treatment of this disease. However, exact information about influence on tear film thickness and corneal residence time of topical lubricants is still sparse, therefore no ideal ...

Phase

Effect of IKERVIS Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe Keratitis

In this phase IV clinical trial the Month 3 visit assessments will be used to assess the efficacy (quality of vision and other parameters) and safety of IKERVIS in DED patients with severe keratitis. To assess the effect on the quality of vision of IKERVIS (1mg/ml ciclosporin) eye drops administered ...

Phase

Topical 2% Ganciclovir Eye Drop for CMV Anterior Uveitis / Endotheliitis

This is non-randomised single armed prospective, cross-sectional, interventional clinical study. 25 patients who are diagnosed with Cytomegalovirus (CMV) anterior segment infection, either uveitis or endotheliitis, at the investigators clinic in Singapore National Eye Centre, who have a positive aqueous real time PCR (RT-PCR) and/or positive tetraplex PCR for CMV and ...

Phase

Using A Novel Classification System in Intravenous GCs Therapy of TAO: A Multi-central Randomized Open Superior Trial

TAO is one of most common extra thyroid manifestation of dysfunctional thyroid disease. Since the morbidity of TAO has been increasing rapidly, Investigators' team is intended to verify the feasibility of the new type of classification system established by the related parameters of orbital MRI scan. Based on classification, investigators ...

Phase

An Open Label Comparing the Short Term Efficacy of Lacrisert

To evaluate the short term effects of LACRISERT. upon fluorescein corneal staining, tear osmolarity and surface topography in human subjects with dry eye disease.

Phase