Kaposi's Sarcoma Clinical Trials

A listing of Kaposi's Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 12 clinical trials
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Background Kaposi sarcoma (KS) tumors grow on the skin, lymph nodes, lungs, bone, and gastrointestinal tract. KS often affects people with immune deficiencies

atazanavir
neutrophil count
lung exam
measurable disease
cancer
  • 12 views
  • 02 Aug, 2021
  • 1 location
Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

Background Kaposi sarcoma (KS) is a cancer most often seen in people with HIV. It causes lesions. These are usually on the skin but sometimes in the lymph nodes

atazanavir
doxorubicin
progressive disease
AIDS
antiretroviral therapy
  • 11 views
  • 02 Aug, 2021
  • 1 location
History of the KSHV Inflammatory Cytokine Syndrome (KICS)

Background KSHV inflammatory cytokine syndrome (KICS) is a newly recognized disease caused by Kaposi sarcoma-associated herpesvirus (KSHV). This virus can cause

lymphoma
cancer
doxorubicin
edema
imaging procedure
  • 81 views
  • 01 Aug, 2021
  • 1 location
Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

. KSHV stands for the Kaposi s sarcoma herpes virus, also called human herpes virus-8, or HHV-8. Researchers want to understand the biology of KSHV-MCD to identify how this disease causes illness and to

chemotherapy regimen
etoposide
investigational treatment
doxorubicin
filgrastim
  • 57 views
  • 02 Aug, 2021
  • 1 location
Siltuximab in Schizophrenia

> In April 2014,siltuxiumab was approved by the U.S. Food and Drug Administration (US FDA) as Sylvant for human immunodeficiency virus (HIV)-negative and human herpesvirus-8 (HHV-8)-negative

antipsychotics
adjunctive treatment
cancer
clozapine
schizophrenia
  • 93 views
  • 02 Aug, 2021
  • 1 location
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

This phase I trial investigates the side effects of cabozantinib and nivolumab in treating patients with cancer that has spread to other places in the body (advanced) and who are undergoing treatment for human immunodeficiency virus (HIV). Cabozantinib may stop the growth of tumor cells by blocking some of the …

cancer
hysterectomy
hiv test
investigational new drug
enzyme-linked immunosorbent assay
  • 0 views
  • 31 Jul, 2021
  • 2 locations
Pembrolizumab in Treating Patients With HIV and Relapsed Refractory or Disseminated Malignant Neoplasms

This phase I trial studies the side effects of pembrolizumab in treating patients with human immunodeficiency virus (HIV) and malignant neoplasms that have come back (relapsed), do not respond to treatment (refractory), or have distributed over a large area in the body (disseminated). Immunotherapy with monoclonal antibodies, such as pembrolizumab, …

solid tumors
BRAF
tumor cells
b-cell lymphoma
AIDS
  • 142 views
  • 01 Aug, 2021
  • 5 locations
Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

This phase II/III trial compares the side effects and activity of oral azacitidine in combination with the standard drug therapy (reduced dose rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone [R-miniCHOP]) versus R-miniCHOP alone in treating patients 75 years or older with newly diagnosed diffuse large B cell lymphoma. R-miniCHOP includes a monoclonal …

lymphoma
chemotherapy regimen
doxorubicin
monoclonal antibodies
marginal zone lymphoma
  • 0 views
  • 01 Aug, 2021
  • 16 locations
Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

The purpose of this study is to understand the impact of sirolimus on idiopathic multicentric Castleman disease.

  • 0 views
  • 01 Aug, 2021
  • 2 locations
Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma

Background Primary effusion lymphoma (PEL) is a rare disease with no standard treatment. Researchers want to see if a drug called lenalidomide along with common chemotherapy drugs may be effective in treating PEL. Objective To test a new treatment for PEL. Eligibility People ages 18 and older with PEL. Design …

vincristine
etoposide
doxorubicin
filgrastim
chemotherapy drugs
  • 9 views
  • 01 Aug, 2021
  • 1 location