Opioid Use Disorder Clinical Trials

A listing of Opioid Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 183 clinical trials
Featured trial
Study Seeking Patients with Opioid Use Disorder

Study Seeking Patients with Opioid Use Disorder

  • 25 Mar, 2021
  • 1 location
Featured trial
A Washington University research study is currently enrolling pregnant or newly post-partum participants.

The purpose of the study is to gain a better understanding of the impact of early life exposure to different substances on infant brain and behavioral development.  

  • 23 Nov, 2020
  • 1 location
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder (VA-BRAVE)

, randomized, controlled trial including 900 Veterans with opioid use disorder (OUD) recruited over 3 years and followed actively for 52 weeks. There are a number of secondary objectives that will be studied

  • 17 Jun, 2022
  • 18 locations
Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder (HOPE MOUD)

In a randomized controlled trial, with 3, 6-month and 1-year follow-up, this application aims to explore whether and how the HOPE intervention can be adapted to increase MOUD uptake among OUD patients, assess the effectiveness of using HOPE to increase MOUD requests, and analyze online community data to improve future …

  • 29 May, 2022
  • 1 location
NIDA-CTN-0100: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

This is a two phase study investigating combinations of pharmacological and behavioral interventions to optimize the treatment of Opioid Use Disorder (OUD). The Retention Phase will assess

  • 14 Oct, 2022
  • 18 locations
Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)

-based and electronic health record (EHR)-integrated Opioid Use Disorder (OUD) Clinical Decision Support (CDS) system to offer expert guidance to primary care providers (PCPs) on the diagnosis and

  • 08 Apr, 2022
  • 3 locations
Smartphones for Opiate Addiction Recovery (SOAR)

Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus recently become a major NIDA policy goal. The 5-minute battery indicates the numerical probability that a patient will …

  • 20 Jun, 2022
  • 1 location
Mobile Peer Support for OUD Recovery (MPS)

The COVID-19 pandemic puts individuals recovering from opioid use disorders (OUDs), an already vulnerable population, at increased risk of overdose due to decreased access to treatment, decreased social support, and increased psychosocial stress. This proposal will test the efficacy of a promising mobile app-based peer support program, compared to usual …

  • 16 Jun, 2022
  • 2 locations
Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics) (MIMIC)

There is an urgent need for effective treatments for patients with opioid use disorder (OUD). This study will train opioid treatment centers in an evidence-based behavioral treatment called

  • 05 Feb, 2022
  • 11 locations
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

This is a multi-centre, open-label RCT at four Emergency Departments (EDs) in British Columbia and Alberta. The purpose of the current study is to compare the effectiveness of buprenorphine/naloxone microdosing and standard dosing take-home induction regimens at enabling patients to successfully complete the induction regimen, and at retaining patients on …

  • 10 Aug, 2021
  • 4 locations