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Alcohol Use Disorder Clinical Trials

A listing of Alcohol Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (312) clinical trials

Clinical Intervention in Alcohol Use Disorder

The relapsing nature of alcoholism is a major obstacle to successful treatment. About 60% of those entering treatment will relapse within one year. To improve treatment outcome, new interventions targeting the underlying brain biomarkers of relapse vulnerability hold significant promise in reducing this critical public health problem. Using resting functional ...

Phase N/A

Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

A 12-week, randomized, double-blind, parallel-group, placebo-controlled adaptive, Drop The Loser (DTL) design clinical trial of citicoline and pregnenolone will be conducted in 199 outpatients with bipolar I or II disorder or schizoaffective disorder (bipolar type) and current alcohol use disorder. Potential participants will be identified and an appointment will be ...

Phase

Testing Doxazosin to Treat Stress Mechanisms in Alcoholism

OBJECTIVES To translate the preclinical evidence from animal models to stress-induced relapse in humans via direct pharmacological antagonism of the noradrenergic system in abstinent alcoholics with doxazosin, an alpha1 noradrenergic receptor blocker. To screen the efficacy of doxazosin to target stress-related relapse mechanisms in abstinent alcoholics as a cost-effective first ...

Phase

NC Young Women's CoOperative (CoOp)

The purpose of this study is to use the seek, test, treat, and retain framework to develop and test the efficacy of a clinic-based, age-appropriate, woman-focused HIV intervention to reduce sexual risk and increase the receipt of health services among 700 young sexually active and drug-using, African American women aged ...

Phase N/A

Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics

Bipolar disorder (BD) is the Axis I psychiatric condition most strongly associated with substance use disorder (SUD); diagnostic co-occurrence is particularly high between BD and alcohol use disorder (AUD). Individuals with co-occurring SUD and BD (SUD+BD) have substantially worse clinical outcomes than those with either BD or SUD alone. Nonetheless, ...

Phase

Facilitating Treatment Entry and Family Planning in Substance-using NICU Mothers

The purpose of this pilot study is to assess whether the hospital-based, adaptive behavioral intervention strategy promotes treatment entry and reduces risk of additional substance-exposed pregnancies (SEPs), as well as HIV and HCV risks among substance-using NICU mothers. Additionally, to assess whether the intervention increases use of professional obstetrical/gynecological resources ...

Phase N/A

Responsible Fatherhood Opportunities for Reentry & Mobility

Individuals with a criminal justice background (either incarcerated or on community supervision) and substance use issues will have the opportunity to enroll in services provided by the Mountain Comprehensive Care Center to focus on enhancing fatherhood and family situations.

Phase N/A

Alkontrol-herbal Effects on Alcohol Drinking

Over the past 15 years, the Behavioral Psychopharmacology Research Lab at McLean Hospital has extensively studied kudzu extract and demonstrated its safety and efficacy in healthy control subjects as well as in heavy binge drinkers. The relative success of our recent outpatient trial of kudzu extract demonstrated a modest decrease ...

Phase

Scaling Up Science-based Mental Health Interventions in Latin America

The investigators plan to launch and evaluate a new mental health service delivery model in Latin America. Specifically, in this new multi-component, mental health service delivery intervention, the investigators propose to: (1) harness mobile behavioral health technology for mental health (with a primary focus on depression and a secondary focus ...

Phase N/A

Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace

Tobacco regulatory policies can have unanticipated consequences; therefore, methods that would permit prospective estimates of the effects of potential tobacco regulations are necessary for the development of tobacco regulatory science. The goal of this project is to experimentally assess how smokers purchase and consume reduced-nicotine cigarettes. In experiment 1, we ...

Phase N/A