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Alcohol Use Disorder Clinical Trials

A listing of Alcohol Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (18) clinical trials

Fish Oil vs. Placebo on Subjective Effects of Alcohol

There have been no studies to date that have examined the relationship between fish oil and alcohol response in humans. The current study was designed to examine the relationship between fish oil and subjective alcohol effects in healthy social drinkers. This project represents a first step in examining the potential …

Phase

Neuroimmune Dysfunction in Alcohol Use Disorder

The research objective of this project is to characterize the role of the neuroimmune system in alcohol use disorder (AUD). The proposed study employs a randomized, double-blind, and placebo-controlled design to examine how neuroinflammation, as measured via neuroimaging [e.g., magnetic resonance imaging (MRI)], relates to alcohol craving, neurocognitive impairment (e.g., …

Phase

The Effect of Dorsolateral Prefrontal Cortex Theta Burst Stimulation on Alcohol Cue Reactivity and Cognitive Control: a Double-blind Sham Controlled Study of Heavy Alcohol Drinkers With a History of Alcohol Related Injury.

Alcohol Use Disorder (AUD) is prevalent, devastating, and difficult to treat. The intransigence of AUD is readily apparent in the Trauma Unit of Wake Forest University Baptist Hospital, wherein 23% of trauma related admissions are associated with alcohol - higher than the national average of 16%. Of these trauma related …

Phase

Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-liability effects of a sub-threshold dose of a commonly used analgesic.

Phase

Brain Imaging in Tobacco Smokers During a Quit Attempt

The primary objective of this basic clinical research study is to examine the role of the alpha7-nicotinic acetylcholine receptors (nAChRs) in tobacco use disorder. nAChRs are the primary site of action for nicotine (the main psychoactive component of tobacco). The most common types of nAChRs are heteromeric nAChRs containing beta2 …

Phase

Reduced Nicotine Cigarettes in Smokers With and Without Alcohol Use Disorder

The current proposal examines response to two RNCs, one with low nicotine content (RNC Low; 0.03mg) and one with moderate nicotine content (RNC Moderate; 0.8mg) in daily smokers with and without ARD. Participants (N = 70) will attend a total of five visits to the laboratory. The first visit will …

Phase

Targeting Orexin to Treat Nicotine Dependence

Tobacco use leads to ~440,000 deaths and a loss of $193 billion every year in the US. This public health and economic crisis continues as no interventions effectively prevent smoking relapse. Between 40-70% of smokers are unable to maintain abstinence and 75% of those who do attain abstinence will relapse …

Phase

We The Village Family Support Study

The primary objective of the proposed Phase I work is to determine the feasibility of delivering Community Reinforcement And Family Training (CRAFT) principles via scalable digital coaching methods and determine its efficacy based on measured outcomes. The Contractor will work with CRAFT experts and researchers to achieve the specific aims …

Phase

Effects of Stress and Drug-cue Exposure (SCM)

Part of this study will be conducted on a residential unit where participants will live for 7 nights over a 2-week period (4 consecutive nights the 1st week and 3 consecutive nights the 2nd week). During that time, participants can't leave the unit unescorted or have visitors. During the inpatient …

Phase

Marijuana Cue-Reactivity & Seeking Behavior in Regular Cannabis Users

This study involves three screening sessions that could last about 3 hours each. Part of this study will be conducted on an inpatient unit where the participant will live for 4 straight nights. During the inpatient stay participants will participant in experimental sessions where they will be asked to smoke …

Phase