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Alcohol Use Disorder Clinical Trials

A listing of Alcohol Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (357) clinical trials

Effects of Repeated Memory Training on Memory Function and Addiction Related Processes

Prospective memory is the ability to implement an intention to the future (e.g. remember to take medication, attend a scheduled meeting), and has receive little attention in addiction. The investigators propose that prospective memory plays a critical, yet unrecognized, role in major human behavior change such as that required in ...

Phase N/A

Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers

The present proposal is intended to answer the call for accelerating drug development by exploring the potential of a novel anticonvulsant, lacosamide as a candidate medication for the treatment of AUD. This drug, which is approved for the treatment of seizure disorders, has unique pharmacological actions that include enhancement of ...


Human Alcohol Seeking Despite Aversion

The long-term goal for this project is to establish a model of alcohol seeking despite aversion (SDA) as a platform for the laboratory testing of novel pharmacologic and behavioral interventions that can be used among those with the highest risk, but who have yet to progress to treatment-resistant drinking. The ...

Phase N/A

Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention

Participants will be 100 individuals (aged 18 to 50) enrolled in outpatient (nonmethadone /buprenorphine) treatment for any substance use disorder (other than PCP) at the Substance Abuse Treatment Unit in New Haven. As the goal of this project is to develop interventions that address self-regulation across multiple disorders, we will ...

Phase N/A

Web-based Addiction Treatment: Cultural Adaptation With American Indians

The purpose of the current study is to evaluate the preliminary efficacy of the Therapeutic Education System-Native Version (TES-NAV) (an efficacious web-delivered psychosocial intervention for substance use disorders adapted with American Indians/Alaska Natives [AI/AN]) to determine whether a future large-scale effectiveness trial is warranted. Specifically, a randomized controlled trial among ...

Phase N/A

Ibudilast and Withdrawal-Related Dysphoria

Alcohol use disorder (AUD) is a prevalent and disabling psychiatric disorder with few, and only moderately efficacious, treatment options. Consequently, the identification of novel treatment targets and the development of rigorous laboratory paradigms to screen and optimize novel therapeutics represents a research priority. Ibudilast (IBUD) is a neuroimmune modulator that ...


Pharmacist Intervention to Reduce Drug-related Readmissions Among the Elderly

At discharge from the hospital, patients that meet the inclusion criteria are offered to participate in the study. At this point the investigators will also gather baseline data through questionnaires on self-reported adherence (MARS-5) and quality of life (EQ-5D). The participants are randomized to the different study arms according to ...

Phase N/A

Behavioral Effects of Drugs: Inpatient (36) (Alcohol Duloxetine and Methylphenidate)

This study will evaluate the behavioral effects of alcohol during maintenance on placebo, duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated human laboratory methods.


MCII for Alcohol Use Disorders

Today's elaborated therapeutic interventions do not ensure sustainability of therapeutic success in alcohol-dependent patients. Thus, it is to develop and implement new therapeutic methods in order to increase regular treatment termination and continuous abstinence during treatment. Mental Contrasting (MC) consists of imaging a desired future and comparing it with obstacles ...

Phase N/A

Cardiac Surgery Peer Support Recovery

Patients admitted with active IE secondary to IV drug use require a myriad of services and will remain hospitalized for a minimum of six weeks. During their hospitalization, infectious disease service assists in developing a treatment plan for the active infection, neurosurgery service evaluates and develops a plan to treat ...

Phase N/A