Alcohol Use Disorder Clinical Trials

A listing of Alcohol Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 37 clinical trials
Neural and Hormonal Influences on Sex Differences in Risk for AUD

The sex gap in alcohol consumption is closing rapidly, due to alarming increases among women. From 2002-2013, Alcohol Use Disorder (AUD) increased 84% for women, compared to 35% for men. As such

  • 0 views
  • 28 Jul, 2021
  • 1 location
Deciphering the Role of Oxytocin in Motivation: an fMRI Study. Part II

The proposed study will investigate the effects of intranasal oxytocin administration on neural activity associated with social and non-social motivation.

oxytocin
  • 163 views
  • 18 Jul, 2021
  • 2 locations
Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

The investigators will compare 3 treatment groups (ketamine plus naltrexone vs. ketamine alone vs. placebo) for treating major depressive disorder (MDD) and alcohol use disorder (AUD) in an 8

heavy drinking
major depressive episode
depression
naltrexone
psychosis
  • 356 views
  • 26 Jul, 2021
  • 1 location
Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)

as PTSD. Given evidence that sexual assault survivors who have low social support or receive negative social reactions to sexual assault disclosure are more likely to experience PTSD and drinking

sexual assault
behavior therapy
violence
assault
  • 0 views
  • 19 Jul, 2021
  • 1 location
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault

Sexual assault can lead to devastating consequences including the development of chronic conditions including posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD). Interventions

sexual assault
exposure therapy
assault
  • 0 views
  • 25 Jul, 2021
  • 1 location
Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders

For this protocol, the investigators plan to collect pilot data to examine sex differences in guanfacine's effect on 1) counteracting stress and stimulation based drinking behavior in the laboratory and 2) improving clinical outcomes during a subsequent treatment phase.

  • 2 views
  • 19 Jul, 2021
  • 1 location
Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse

This project aims to evaluate the potential rapid and sustained antisuicidal and antidepressant effects of a single intranasal dose of ketamine in inpatients during a mood episode in Major Depressive Disorder (MDD) or Bipolar Disorder (BD) with or without comorbid recent abuse of alcohol.

suicidal
major depressive episode
major depressive disorder
depressive episode
depression
  • 719 views
  • 18 Jul, 2021
  • 1 location
COMT Inhibition Among Individuals With Comorbid AUD/ADHD

The purpose of this study is to determine whether the catechol-O-methyltransferase (COMT) inhibitor tolcapone, relative to placebo, affects response to alcohol, decision-making, brain activation associated with alcohol cue reactivity, response inhibition, and selective attention, or alcohol drinking.

hyperactivity
  • 0 views
  • 28 Jul, 2021
  • 1 location
Brief ROC Training Effects on Alcohol Drinking

The goal of the proposed study is to examine whether a single session of training in regulation of craving (ROC-T) affects alcohol drinking. The study will consist of (1) a basic screening (phone and/or online) and an in-person visit, to determine eligibility and conduct pre-intervention baseline assessments; (2) a training …

heavy drinking
  • 7 views
  • 23 Jul, 2021
  • 1 location
Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19

, a drug approved for treating alcoholism and opiate addiction, as well as Ketamine, a drug approved as an anesthetic, may be able to interrupt the inflammation that causes the worst COVID-19 symptoms

coronavirus
covid-19
coronavirus infection
  • 226 views
  • 21 Jul, 2021
  • 1 location