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Alcohol Dependence Clinical Trials

A listing of Alcohol Dependence medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (267) clinical trials

Mindfulness Meditation for the Treatment of Women With Comorbid PTSD and SUD

This randomized controlled pilot study will evaluate the feasibility and preliminary efficacy of MBRP plus usual community treatment as usual (TAU) compared to TAU alone (TAU) for women with substance use disorders(SUD) and PTSD enrolled in community substance abuse treatment. Participants will be randomized to eight weekly 90-minute, mixed individual ...

Phase N/A

Prenatal Cocaine Nasal Oxytocin and Maternal Psychophysiology

Participation for mothers when they are 3-6 months postpartum includes: Visit 1: Questionnaires and interviews about participants' health, pregnancy, moods, psychological history and drug use during pregnancy and postpartum. Visit 2: Pregnancy & drug tests (results are confidential), blood samples and vital signs, video-taped mother-infant interaction, speech task, instruction re: ...

Phase

New Therapeutic Strategies for Inhibitory Control in Alcoholism

The main purpose of this study is to demonstrate the efficacy of two different treatments for inhibitory control improvement (measured by the modified Stop signal task): a behavioral treatment based on Retrieval-Extinction Learning, through the AAT (Alcohol Approach Avoiding Task) and a treatment based on the neuromodulation of prefrontal cortex ...

Phase N/A

Charleston ARC Clinical Project 4- Cortical rTMS as a Tool to Change Craving and Brain Reactivity to Alcohol Cues

SPECIFIC AIMS Alcohol Use Disorders (AUDs) are prevalent, devastating, and difficult to treat. High relapse rates are likely due to factors that affect limbic and executive circuits in the brain, including vulnerability to salient cues and loss of cognitive control. Limbic drive and executive control are regulated by two cortical-subcortical ...

Phase N/A

Pharmacogenetics of Naltrexone for Stimulant Abuse

A recent meta-analysis concluded that the OPRM1 A118G SNP (rs1799971) significantly moderates the treatment efficacy of Naltrexone (NTX) in treating alcohol abuse, increasing the treatment efficacy by over 2-fold among G-allele carriers (AG/GG). The proposed application would be the first to investigate the moderating effect of this genotype in the ...

Phase

Treatment With Quetiapine for Youth With Substance Use Disorders and Severe Mood Dysregulation

The purpose of this study is to determine whether quetiapine is effective in the treatment of youth with co-occurring substance use disorders and severe mood dysregulation.

Phase

Effects of Expectation Medication and Placebo on Objective and Self-rated Performance

Introduction: During the last decade, neuropsychiatric impairments in adults have more often been observed. Requests for neuropsychiatric investigations, especially concerning Attention Deficit Hyperactivity Disorder (ADHD) has increased. The core ADHD symptoms in adults include a frequent and persistent pattern of inattention/distractibility and/or hyperactivity/impulsivity (Adler 2004; Adler & Chua 2002; McGough ...

Phase

Prevention and Risk: Treatment With a New Emphasis on Relationships

This study aims to evaluate a individual-focused intervention with an integrated focus on drug use and HIV prevention, including uptake of and adherence to PrEP. The investigators will recruit a sample of 240 partnered individuals. Recruitment occurs using a mix of in-person and Internet recruitment. Outreach workers will visit bars ...

Phase N/A

PCORI Integrated Care (IC) Models for Patient-Centered Outcomes

Study aims. Given the documented need for valuable information about system-level features that can be used to effectively and efficiently support adults in living well with MCC, this study is designed to achieve the following aims: Aim 1: Compare the effectiveness of High-Touch, High-Tech, and Usual Care on primary outcomes ...

Phase N/A

Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention

HIV/STI and drug abuse remain significant public health priorities in the US and youth are disproportionately affected. Youth between the ages of 15 - 24 constitute 25% of the sexually experienced population, yet account for 46% and 50% of HIV infections and new STIs, respectively. National surveillance data indicate that ...

Phase N/A