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Alcohol Dependence Clinical Trials

A listing of Alcohol Dependence medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (22) clinical trials

Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use

Objectives: Illicit drug use affects tens of millions of Americans and costs nearly $200 billion annually in health care costs and lost productivity. Cocaine dependence accounts for 25% of reported lifetime drug dependence though few successfully abstain with treatment. For efforts toward positive long-term outcomes, it is imperative to identify ...

Phase

Cannabis and Tobacco Co-use Study

Cannabis co-use among tobacco users is exceedingly common and rates of co-use appear to be increasing among adults in the US, which is consistent with overall increases in cannabis use rates among US adults. Given the current cannabis landscape, further increases in cannabis use are likely and may result in ...

Phase

The Kentucky Viral Hepatitis Treatment Study

The overarching goal of the Kentucky Viral Hepatitis Treatment Project (KeY Treat) is to increase access to treatment for the hepatitis C virus (HCV) in a rural Appalachian community in the midst of the opioid/HCV syndemic. This study seeks to examine whether removing barriers associated with accessing direct-acting antivirals (DAAs) ...

Phase

Topiramate Treatment of Alcohol Use Disorders in African Americans

Objective(s): Despite having lower rates of drinking and heavy drinking than European Americans (EAs), African Americans (AA) have significantly higher rates of mortality from a variety of alcohol-related conditions, including liver cirrhosis, accidents, and violence. The current proposal aims to improve alcohol treatment in AA Veterans, who comprise 12% of ...

Phase

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

This clinical study is a phase IV, prospective, open-label study that is being conducted in 25 participants over the age of 18 on stable antiretroviral therapy with documented HIV viral suppression who have received opioid substitution therapy (OST) for at least three months. The study is designed to assess the ...

Phase

Addiction HIV and Tuberculosis in Malaysian Criminal Justice Settings

Part A: All newly admitted prisoners (80-120 new inmates on admission days) undergo a complete assessment, including a brief exam and mandatory rapid HIV test by the prison medical unit. Each prisoner waiting to be evaluated will be invited for participation in TB screening activities (not currently part of standard ...

Phase

Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder

Childhood ADHD and comorbid oppositional defiant disorder (ODD) and conduct disorder (CD) are considered risk factors for subsequent substance abuse, and youth with both ADHD and ODD/CD are at greatest risk. However, the effects of treatment of ADHD with stimulant medications such as methylphenidate (MPH) and mixed amphetamine salts (MAS) ...

Phase

Antibiotic Prophylaxis in Patients Undergoing GVO

Gastric varices is not uncommon is patients with chronic liver diseases including liver cirrhosis and hepatocellular carcinoma. Occurrence of gastric varices (GV) rupture is less often than esophageal varices (EV) but it is characteristic of higher rebleeding rate and mortality and represents an even tougher problem than EV hemorrhage. Endoscopic ...

Phase

HCV Seek Test and Rapid Treatment for Young PWID

ST&RT is a randomized openlabel clinical trial in which 54 HCV infected PWID between ages 18 and 29 will be randomized to either receive the sameday treatment initiation of the FDAapproved fixed dose combination of sofosbuvir 400mg and velpatasvir 100mg (SOF/VEL) with follow up and medical monitoring at a community ...

Phase

Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy

Prospective randomized control trial. There will be 2 groups, control group and the intervention group. The control group will receive the standard of care used for NAS treatment currently in Cooper Hospital NICU and transitional nursery. Morphine is used as the standard treatment and if the withdrawal symptoms are not ...

Phase