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Preeclampsia Clinical Trials

A listing of Preeclampsia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (118) clinical trials

NYU Winthrop Hospital Clinical Trials Center is seeking research participants who are 18 years old or older, who are pregnant and between 28 and 37 weeks gestation and are interested in participating in a clinical trial.  Participants will be asked to provide blood and urine sample(s) to be used to ...

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Preeclampsia is a complication of pregnancy. Preeclampsia may occur from 20 weeks’ pregnancy through the delivery and postpartum period.  Preeclampsia does not occur in every pregnant woman. It is thought that preeclampsia occurs in about 3 to 5 out of a total of 100 pregnant women. A higher number of ...

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An observational study evaluating antithrombin III (ATIII), activity in women with PE at 23-0 to 30-6/7 weeks. Those with AT activity at < 70% will be compared to those with AT ≥ 70% with respect to latency period after enrollment and maternal / perinatal outcomes. An interim analysis will be ...

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Phenylephrine Versus Ephedrine in Pre-eclampsia

Phenylephrine administration is associated with reductions in CO and SctO2 compared with ephedrine when used for blood pressure management in women with pre-eclampsia undergoing cesarean delivery under spinal anesthesia.


Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension

BUMP 1 will randomise 2262 women at higher risk of hypertension in pregnancy into usual care or self-monitoring. BUMP 2 will randomise 512 women with hypertension in pregnancy (including chronic hypertension) into usual care or self-monitoring. Women in BUMP 1 will move into BUMP 2 if they develop hypertension. Women ...

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Non-invasive Versus Invasive Blood Pressure Measurement in the Super Morbidly Obese Parturient With Severe Preeclampsia

A morbidly obese [Body Mass Index (BMI) 45 kg/m2] pregnant woman is at singular risk for all the complications of pregnancy, most notably preeclampsia (PE). Furthermore a woman who is already chronically hypertensive is likely to develop superimposed PE . Uncontrolled systolic hypertension in pregnancy prompts placental abruption, hemorrhagic stroke, ...

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Impedance Cardiography to Decrease the Risk of Preeclampsia

Impedance cardiography helps determine whether vasoconstriction or an elevated cardiac output is occurring. The test is easy to perform and non invasive. The treatment for an elevated cardiac output in pregnancy is a beta-blocker while a vasodilator is used for vasoconstriction. If a beta-blocker is given to someone that vasoconstricted, ...

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sFlt-1:PlGF Ratio in Diagnosing Superimposed Preeclampsia

Subjects with a diagnosis of chronic hypertension made prenatally or in the first 20 weeks of pregnancy (+/- medical therapy). The clinical diagnosis of preeclampsia will follow the current criteria outlined by ACOG (American College of Obstetricians & Gynecologists) 10. Study/Project Procedures: Blood draw at the time of initial presentation ...

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Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development

The overall objective of this study is to determine whether the anti-angiogenic environment of preeclampsia results in pulmonary and vascular dysfunction in infants. Specifically, study investigators hypothesize that the anti- angiogenic environment of preeclampsia will impair pulmonary development and promote vascular dysfunction in infants. Furthermore, study investigators hypothesize that circulating ...

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