Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 189 clinical trials
Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia (EMPOWER)

Hyponatremia is the most common electrolyte derangement occurring in hospitalized patients. It is usually classified as hypovolemic, euvolemic or hypervolemic. The most common aetiology of euvolemic hyponatremia is the syndrome of inappropriate antidiuresis (SIAD). Hypervolemic hyponatremia is common in patients with congestive heart failure (CHF) (10-27%) and liver cirrhosis (up …

diabetes
heparin
heart failure
vasopressin
sglt2
  • 0 views
  • 24 May, 2022
  • 2 locations
Use of Direct Peritoneal Resuscitation in High-risk Liver Transplant Recipients

This study is being conducted to assess the safety of Direct Peritoneal Resuscitation (DPR) in high-risk liver transplant patients. The investigators want to also identify if this method of recovery after large surgery has the same benefits in liver transplant patients as have been appreciated in other surgical patients. The …

liver transplant
dialysis
  • 0 views
  • 23 Mar, 2022
Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose (PEARL)

Rationale: Hepatic encephalopathy (HE) is a major and common complication in patients with liver cirrhosis. HE can be classified in the extensive range of neurocognitive deterioration as minimal HE (MHE), covert HE (grade I), or overt HE (OHE, grade II-IV). Liver cirrhosis is the most common cause of portal hypertension …

electrolytes
fibroscan
diuretics
endoscopy
furosemide
  • 14 views
  • 24 Mar, 2022
  • 6 locations
Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation

Comparison of biliary complications in right lobe living donor liver transplantation patients undergoing biliary reconstructions using microscope versus surgical loupes .

liver transplant
  • 0 views
  • 06 Apr, 2022
  • 1 location
Prospective Study for the Application of Cytosorb in Critically Ill Patients

Cytosorb, which has a CE certification for the indications hyperinflammation, rhabdomyolysis and liver failure and is therefore frequently used in patients with sepsis, polytrauma and acute liver failure

  • 0 views
  • 15 Jun, 2021
  • 1 location
Goal-Directed Hemostatic Resuscitation Trial in ACLF Induced Coagulopathy (GOODHEART-ACLF)

In this project, we plan to evaluate whether a new, rotational thromboelastometry-guided algorithm (ROTEM) to guide hemostatic resuscitation decreases the use of allogeneic blood products, the total amount of bleeding, transfusion related side effects, thromboembolic complications and costs. Its effect on each patient's post-operative hemostatic profile is also measured. We …

prothrombin
hemostatic
  • 0 views
  • 14 May, 2022
  • 1 location
Mild Hypothermia and Acute Kidney Injury in Liver Transplantation (MHALT)

Acute kidney injury (AKI), or worsening kidney function, is a common complication after liver transplantation (20-90% in published studies). Patients who experience AKI after liver transplantation have higher mortality, increased graft loss, longer hospital and intensive care unit stays, and more progression to chronic kidney disease compared with those who …

anesthesia
chronic kidney disease
liver transplant
nephropathy
acute renal failure
  • 38 views
  • 04 Mar, 2022
  • 3 locations
Growth Hormone in Decompensated Liver Cirrhosis

-long immunosuppression. In addition to complications due to portal hypertension and hepatic insufficiency, decompensated cirrhosis is associated with malnutrition, sarcopenia, immune dysfunction

jaundice
insulin
hypertension
cirrhosis
encephalopathy
  • 0 views
  • 23 Apr, 2022
  • 1 location
Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics and Safety of Lorlatinib

This is a post approval requirement to study the effect of moderate and severe hepatic impairment on the pharmacokinetics of lorlatinib.

Accepts healthy volunteers
  • 0 views
  • 23 May, 2022
  • 3 locations
A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB

starvation and dehydration; however, intravenous (IV) nutrition can lead to complications including liver failure. Tube feeding directly to the small intestine avoids the complications of IV nutrition, but

small intestine
total bilirubin
intestinal resection
gastrointestinal disease
tube feeding
  • 0 views
  • 09 Feb, 2022
  • 1 location