Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 192 clinical trials
The Effects of Double Plasma Molecular Adsorption System in Acute on Chronic Liver Failure Patients

Acute liver failure patients posed high mortality rate despite receiving standard therapy. The severity and mortality even higher in patients with underlying liver disease. Acute liver failure

  • 0 views
  • 23 Apr, 2022
  • 1 location
Randomized Trial of Hepaticojejunostomy Versus Duct-to-duct Anastomosis in Right Lobe Living Donor Liver Transplantation

The scarcity of deceased donor organ supply has driven the practice of living donor liver transplantation (LDLT). Right lobe LDLT (RLDLT) has developed over the last 10 years to extend the benefit of LDLT to adult patients. With technical refinement, the results have significantly improved but bile duct complications remain …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Pharmacokinetic Study of Icenticaftor in Participants With Hepatic Impairment

The primary purpose of this study is to evaluate the effect of hepatic impairment on the systemic pharmacokinetics, safety, and tolerability of icenticaftor in participants with varying degrees of hepatic impairment.

hepatic impairment
liver disease
Accepts healthy volunteers
  • 2 views
  • 22 Mar, 2022
  • 1 location
Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit

. Early physical rehabilitation has shown benefit in ICU settings, but has not been studied in ICU patients with acute and chronic liver failure. Cycle ergometry, or stationary cycling in passive and

liver disease
  • 0 views
  • 19 Feb, 2022
  • 1 location
Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation

This is a prospective, multi-center, controlled, randomized, pivotal study to evaluate the safety and effectiveness of the VitaSmart Liver Machine Perfusion System by comparing clinical outcomes in patients undergoing liver transplantation with ex-vivo liver preservation using static cold storage (SCS) followed by hypothermic oxygenated machine perfusion (HOPE) versus SCS only.

carcinoma
  • 0 views
  • 22 Mar, 2022
  • 1 location
Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic Function

This multi-center, open-label, parallel-controlled, single-dose Phase 1 study is being conducted to directly characterize the pharmacokinetic (PK) profiles and safety of Jaktinib following administration of a single oral dose in subjects with varying degrees of hepatic impairment compared to healthy matched control subjects with normal hepatic function(matched by age, weight, …

body mass index
hepatic impairment
cirrhosis
liver disease
fibroscan
  • 0 views
  • 10 Dec, 2021
  • 1 location
Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia

End stage liver disease is prone to thrombocytopenia. This study is a multi-center, randomized, prospective, randomized controlled Phase IV Clinical trial to discuss the Efficacy and Safety of Avatrombopag in Patients with End-stage Liver Disease and Thrombocytopenia.

platelet count
cirrhosis
liver disease
avatrombopag
  • 0 views
  • 16 Jun, 2021
  • 1 location
Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy

Efficacy and Safety of Nitazoxanide in preventing recurrence of Hepatic Encephalopathy.

rifaximin 550 mg
encephalopathy
rifaximin
  • 4 views
  • 18 Feb, 2022
  • 1 location
Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

Readmission rates for patients with hepatic encephalopathy due to end stage liver disease are high. Hyperammonemia contributes significantly to encephalopathy and occurs because of impaired hepatic ureagenesis and increased skeletal muscle proteolysis. We propose a randomized, 6-month nutritional intervention in cirrhotic patients who have had at least 1 admission for …

hyperammonemia
protein supplement
cirrhosis
liver disease
encephalopathy
  • 38 views
  • 18 Feb, 2022
  • 1 location
Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy

The purpose of the study is to evaluate the safety of Rifaximin or placebo in subjects with severe hepatic impairment and Hepatic Encephalopathy.

hepatic impairment
meld score
liver disease
encephalopathy
rifaximin
  • 328 views
  • 24 Jan, 2022
  • 21 locations