Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 216 clinical trials
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Role of Fecal Microbiota in Predicting Graft Rejection and Sepsis Among Recipients of Living Donor Liver Transplant in First Year.

often correlated to complications like-endotoxemia, sepsis, worsening liver failure and poor survival. This has led to consider fecal microbiota modulation as an emerging therapy. Liver transplant and

cirrhosis
endotoxemia
hepatitis
liver transplant
  • 0 views
  • 10 Oct, 2021
  • 1 location
None
The Efficacy and Safety of Nucleos(t)Ide Analogues in the Treatment of HBV-related Acute-on-chronic Liver Failure

HBV-related acute-on-chronic liver failure (ACLF) is a clinical syndrome defined as acute hepatic insult with diagnosed or undiagnosed chronic liver disease. Current clinical guidelines advocate

tenofovir alafenamide
antiviral drugs
tenofovir
jaundice
hepatitis b surface antigen
  • 6 views
  • 22 Jan, 2021
  • 7 locations
None
Longitudinal Study of Mitochondrial Hepatopathies

The specific aims of this study are (1) to determine the clinical phenotypes and natural history of hepatic RC and FAO disorders, (2) to determine the correlation between genotype and phenotype, (3) to determine if circulating biomarkers reflect diagnosis and predict liver disease progression and survival with the native liver, …

chronic liver failure
mitochondrial hepatopathy
liver failure
cirrhosis
portal hypertension
  • 34 views
  • 08 Sep, 2021
  • 20 locations
None
MERTK Signalling in Monocytes/Macrophages in Patients With Liver Disease

cirrhosis at different stages of disease (Child A, B, C, acute decompensation, acute-on-chronic liver failure (ACLF)) and in comparison to patients with acute liver failure and to healthy controls.

liver disease
acute hepatic failure
liver failure
monocytes
acute on chronic liver failure
  • 0 views
  • 25 Nov, 2021
  • 4 locations
None
Assessment of Remnant Liver Function in ALPPS by Gd-EOB-DTPA Enhanced MRI

Insufficient future liver remnant (FLR), which may render post-hepatectomy liver failure, is one of the major obstacles for performing liver resection for patients with liver malignants

  • 0 views
  • 26 Mar, 2021
  • 1 location
None
Role of MRI in Detection of Minimal Hepatic Encephalopathy

Introduction Liver cirrhosis (LC) is irreversible fibrosis of the liver (1) and it remains a public health problem. One of the complications of the cirrhosis is hepatic encephalopathy (HE) which is defined as brain dysfunction caused by liver insufficiency. Pathophysiological mechanisms of HE are complex and multifactorial. Recognition of beginning …

  • 0 views
  • 23 Jan, 2021
None
Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation

The overarching objective of the research program entitled ELIPTO (Enhancing Liver Insufficiency and Postoperative Transplantation Outcomes) (www.elipto.ca) is to improve the perioperative care of liver transplant recipients. One of this program's purposes is to better define the effects of intraoperative hemodynamic management on postoperative outcomes in adult liver transplant recipients. …

cirrhosis
liver disease
liver transplant
  • 9 views
  • 25 Nov, 2021
  • 1 location
None
Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases

In this observational study, data from patients treated with the antibiotic ceftobiprole in the past will be collected. The sponsor of the study is Correvio International Srl, based in Switzerland. Correvio has committed to the health authorities to obtain further information on possible side effects especially in patients suffering from …

antibiotics
liver failure
renal failure
absolute neutrophil count
renal impairment
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Hepatectomy Risk Assessment With Functional Magnetic Resonance Imaging

Liver resection remains the only curative option for primary or metastatic liver cancer, but a more accurate prediction of post-hepatectomy liver failure (PHLF) is needed to further reduce

  • 0 views
  • 03 Feb, 2021
  • 1 location
None
NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients

minutes in length. Multimodality high-resolution physiological signals will be collected from brain injured patients: traumatic brain injury, subarachnoid and intracerebral hemorrhage, liver

stroke
traumatic brain injury
  • 12 views
  • 10 Nov, 2021
  • 2 locations