Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 210 clinical trials
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Risk Factors for Acute Kidney Injury in Critically Ill Patients With Acute-on-Chronic Liver Failure

Acute kidney injury (AKI) is one of the most important factors associated with increased mortality in patients with acute-on-chronic liver failure (AoCLF). Early identification and treatment of

  • 0 views
  • 23 Sep, 2021
None
Flicker App for Minimal Hepatic Encephalopathy

There is a great unmet clinical need for improved screening for MHE in patients with cirrhosis. We will demonstrate that the Flicker-App can be used in clinic as well as at home by patients with cirrhosis to measure CFF, a proven screening test for MHE. We will optimize the protocol, …

encephalopathy
screening procedures
cirrhosis
minimal hepatic encephalopathy
flicker
  • 0 views
  • 25 Jan, 2021
  • 1 location
None
Role of Fecal Microbiota in Predicting Graft Rejection and Sepsis Among Recipients of Living Donor Liver Transplant in First Year.

often correlated to complications like-endotoxemia, sepsis, worsening liver failure and poor survival. This has led to consider fecal microbiota modulation as an emerging therapy. Liver transplant and

cirrhosis
hepatitis
endotoxemia
liver transplant
  • 0 views
  • 10 Oct, 2021
  • 1 location
None
The Efficacy and Safety of Nucleos(t)Ide Analogues in the Treatment of HBV-related Acute-on-chronic Liver Failure

HBV-related acute-on-chronic liver failure (ACLF) is a clinical syndrome defined as acute hepatic insult with diagnosed or undiagnosed chronic liver disease. Current clinical guidelines advocate

encephalopathy
prothrombin
tenofovir
hepatic failure
fumarate
  • 6 views
  • 22 Jan, 2021
  • 7 locations
None
Longitudinal Study of Mitochondrial Hepatopathies

The specific aims of this study are (1) to determine the clinical phenotypes and natural history of hepatic RC and FAO disorders, (2) to determine the correlation between genotype and phenotype, (3) to determine if circulating biomarkers reflect diagnosis and predict liver disease progression and survival with the native liver, …

encephalopathy
prothrombin
liver failure
hepatic failure
mitochondrial hepatopathy
  • 34 views
  • 08 Sep, 2021
  • 20 locations
None
MERTK Signalling in Monocytes/Macrophages in Patients With Liver Disease

cirrhosis at different stages of disease (Child A, B, C, acute decompensation, acute-on-chronic liver failure (ACLF)) and in comparison to patients with acute liver failure and to healthy controls.

encephalopathy
monocytes
liver failure
hepatic failure
hepatectomy
  • 0 views
  • 26 Jan, 2021
  • 4 locations
None
Assessment of Remnant Liver Function in ALPPS by Gd-EOB-DTPA Enhanced MRI

Insufficient future liver remnant (FLR), which may render post-hepatectomy liver failure, is one of the major obstacles for performing liver resection for patients with liver malignants

  • 0 views
  • 26 Mar, 2021
  • 1 location
None
Role of MRI in Detection of Minimal Hepatic Encephalopathy

Introduction Liver cirrhosis (LC) is irreversible fibrosis of the liver (1) and it remains a public health problem. One of the complications of the cirrhosis is hepatic encephalopathy (HE) which is defined as brain dysfunction caused by liver insufficiency. Pathophysiological mechanisms of HE are complex and multifactorial. Recognition of beginning …

  • 0 views
  • 23 Jan, 2021
None
Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation

The overarching objective of the research program entitled ELIPTO (Enhancing Liver Insufficiency and Postoperative Transplantation Outcomes) (www.elipto.ca) is to improve the perioperative care of liver transplant recipients. One of this program's purposes is to better define the effects of intraoperative hemodynamic management on postoperative outcomes in adult liver transplant recipients. …

cirrhosis
liver disease
liver transplant
  • 9 views
  • 24 Sep, 2021
  • 1 location
None
Hepatectomy Risk Assessment With Functional Magnetic Resonance Imaging

Liver resection remains the only curative option for primary or metastatic liver cancer, but a more accurate prediction of post-hepatectomy liver failure (PHLF) is needed to further reduce

  • 0 views
  • 03 Feb, 2021
  • 1 location