Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 189 clinical trials
Real World Study of End-stage Liver Disease in China

The aims of this study are exploring the current situation of end-stage liver disease in China, and the optimization of diagnosis and treatment. Liver cirrhosis often accompanied by a series of complications. Therefore, it is necessary to standardize the diagnosis and treatment of liver cirrhosis and its complications. End-stage liver …

liver failure
hepatocellular carcinoma
liver disease
  • 14 Feb, 2022
  • 1 location
Functional Assessment in Liver Transplantation (FrAILT)

This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive …

functional assessment
liver transplant
liver disease
  • 12 May, 2022
  • 7 locations
Intraoperative Normal Saline Administration and Acute Kidney Injury in Patients Undergoing Liver Transplantation

The investigators attempted to investigate the association of the type of crystalloid administered during liver transplantation with postoperative clinical outcomes. The investigators hypothesized that the greater amount of normal saline or half-saline administered during liver transplantation might be associated with the increased risk of acute kidney injury compared to the …

  • 02 Jun, 2022
  • 1 location
Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106)

Hepatic encephalopathy (HE) is a common complication of cirrhosis, which seriously damages the life quality of patients. As the disease progresses, 50-80% of patients with cirrhosis develop HE. Minimal hepatic encephalopathy (MHE) is a manifestation of HE, in which the patient usually has no obvious clinical symptoms and can only …

Accepts healthy volunteers
psychometric testing
minimal hepatic encephalopathy
  • 25 Mar, 2022
  • 2 locations
Association Between the Use of Pulmonary Artery Catheter and Clinical Outcomes After Liver Transplantation

The investigators attempted to evaluate whether the use of PAC is associated with better clinical outcomes after liver transplantation compared with the case without PAC.

  • 27 Jul, 2022
  • 1 location
VICIS - Vienna Cirrhosis Study (VICIS)

Patients with advanced chronic liver diseases treated at the Vienna General Hospital of the Medical University of Vienna will be offered to participate in this prospective observational trial. Clinical parameters and laboratory parameters will be recorded for all patients and patients will undergo a regular follow-up schedule with clinical visits …

liver disease
  • 25 Feb, 2022
  • 1 location
A Study of AARC Standards on Diagnosis and Treatment of Patients With HBV-ACLF in China (AARC China Study)

The AARC China Study is to establish a widely recognized and harmonized standard of patients with HBV-ACLF in the Asia Pacific region.

bacterial infection
pleuritic pain
  • 15 Feb, 2022
  • 1 location
Characterization and Pathogenesis of ACLF

This single-center prospective observational study aims at characterization of pathogenesis of ACLF. There will be three different cohorts investigated with the main endpoint mortality in these groups. SAPIENT = Sepsis ACLF patients, to investigate the differences between ACLF and sepsis in cirrhosis PROACT = Portal mediators as ACLF Targets, to …

  • 05 Aug, 2021
  • 1 location
Hepatotoxicity Related to Protein Kinase Inhibitors

Although protein kinase inhibitors (PKIs) have proved effective in treating many cancers, few patients receiving PKIs may experience rare but life-threatening hepatotoxicity such as hepatic

  • 07 Jul, 2022
  • 1 location
Precise Profiling of Liver Disease Patients With DPMAS Therapy Treating Optimal Patients and Achieving Hard Endpoint (PADSTONE Study)

Acute-on-chronic liver failure (ACLF) is life-threaten syndrome in patients with chronic liver disease. In China, hepatitis B virus (HBV) is the main etiology of cirrhosis and HBV-ACLF is

  • 29 Nov, 2021
  • 1 location