Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 180 clinical trials
Correlation of Liver and Spleen Stiffness by RT-2D-SWE and Severity of Portal Hypertension by HVPG

secondary aims are: 1) to analyse clinical outcomes of these patients in order to determine if LS and/or SS as assessed by RT-2D-SWE might predict adverse outcomes (liver decompensation, death or HCC

  • 21 Jan, 2021
  • 1 location
Organ-specific Responses to Atezolizumab Plus Bevacizumab in Advanced HCC

Hepatocellular carcinoma (HCC) is one of the most frequent causes of cancer-related deaths globally and in Korea. Many patients diagnosed at advanced stage, and systemic therapy is mainstay of treatment in patients with advanced HCC. However, immune-checkpoint inhibitor (ICI) monotherapy did not significantly improve overall survival in phase III studies. …

  • 05 Aug, 2021
  • 1 location
NETs: Protection or Harm in Neonatal Inflammation or Infection

This is a prospective in vitro cell biology study of polymorphonuclear leukocyte (PMN) protein synthesis in response to PAF. PMNs from cord blood of premature human infants at risk for NEC (birth weight between 501 - 1500 grams) and PMNs from cord blood of healthy term infants will be isolated …

Accepts healthy volunteers
  • 23 Jan, 2022
  • 1 location
Vascular Liver Disease Evaluation Follow Up and Non-Invasive Diagnostics Program

Background Vascular liver disorders (VALDI) are rare diseases, for which knowledge on risk factors, appropriate methods of diagnosis, effect of therapy and prognosis still need to be improved. Aim of the study This project aims to study risk factors, methods of detection, therapy and prognosis in order to elaborate and …

  • 10 Oct, 2021
  • 1 location
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs

Management of ACLF is mainly supportive. The poor outcomes lead physicians to consider liver transplantation as an option, even if controversial. In sicker recipients, LT results in immediate survival, but poor medium-term survival rates in some studies. The scarcity of deceased donors obliges to maximize LT success. Alternative strategies, as …

  • 13 Aug, 2021
  • 83 locations
Real World Study of End-stage Liver Disease in China

The aims of this study are exploring the current situation of end-stage liver disease in China, and the optimization of diagnosis and treatment. Liver cirrhosis often accompanied by a series of complications. Therefore, it is necessary to standardize the diagnosis and treatment of liver cirrhosis and its complications. End-stage liver …

liver failure
hepatocellular carcinoma
  • 23 Jan, 2021
  • 1 location
Functional Assessment in Liver Transplantation

This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive …

liver disease
functional assessment
liver transplant
  • 08 Jul, 2021
  • 11 locations
Fibrinogen and Intraoperative Bleeding in Liver Transplant

Liver transplantation is the only treatment for end-stage liver disease. It is a high-risk surgery that can cause heavy intraoperative bleeding. Bleeding and transfusions of blood products are themselves associated with several postoperative complications. Few data have suggested beneficial interventions that can decrease this bleeding. Such interventions are necessary in …

liver disease
liver transplant
  • 25 Jul, 2021
  • 2 locations
A Study of AARC Standards on Diagnosis and Treatment of Patients With HBV-ACLF in China (AARC China Study)

The AARC China Study is to establish a widely recognized and harmonized standard of patients with HBV-ACLF in the Asia Pacific region.

bacterial infection
spontaneous bacterial peritonitis
gastrointestinal hemorrhage
fungal infection
  • 24 Jan, 2021
  • 1 location
VICIS - Vienna Cirrhosis Study

Patients with advanced chronic liver diseases treated at the Vienna General Hospital of the Medical University of Vienna will be offered to participate in this prospective observational trial. Clinical parameters and laboratory parameters will be recorded for all patients and patients will undergo a regular follow-up schedule with clinical visits …

liver disease
  • 08 Sep, 2021
  • 1 location