Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 192 clinical trials
Periodontal Therapy and Oral-gut-hepatic Axis Cirrhosis: a Randomized Controlled Trial

, oral dysbiosis and the prognosis of cirrhosis remains crucial with relevance to situations like acute-on-chronic liver failure and other inflammation-related adverse events.

liver transplant
cirrhosis
encephalopathy
liver disease
severe periodontal disease
  • 9 views
  • 03 Mar, 2022
  • 1 location
HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)

patients with hemorrhagic shock and/or liver failure caused by variceal bleeding face a mortality of 5-20%. Hepatic venous pressure gradient (HVPG) is the recommended golden standard for portal

  • 0 views
  • 22 Aug, 2021
  • 4 locations
Safety and Efficacy of Fecal Microbiota Transplantation

The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease states. Fecal microbiota transplantation (FMT), defined as infusion of feces from healthy donors …

alcoholism
encephalopathy
metabolic syndrome
colitis
antibiotic therapy
  • 427 views
  • 23 Mar, 2022
  • 1 location
Impact of Dietary Assessment and Intervention on Outcomes in Liver Cirrhosis Patients

Malnutrition and reduced muscle mass have been associated with poor outcomes in many disease conditions including severe inflammatory bowel disease, liver failure and cancers. Studies have shown

shear wave elastography
cirrhosis
encephalopathy
cytokines
spontaneous bacterial peritonitis
  • 0 views
  • 10 May, 2022
  • 1 location
Role of Cytosorb in Left Ventricular Assist Device Implantation

Mechanical circulatory support, specifically implantable continuous flow left ventricular assist device (CF-LVAD) therapy has been established as a viable treatment for rapidly deteriorating patients suffering from end stage heart failure either as bridge or alternative to heart transplantation. However, a large proportion of these patients experience severe complications in the …

heart failure
heart transplantation
  • 0 views
  • 26 Jan, 2021
  • 1 location
Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors

This phase III trial studies the effect of tenofovir alafenamide in preventing liver complications in patients with current or past hepatitis B virus (HBV) who are receiving anti-cancer therapy for solid tumors. People with chronic or past HBV who are undergoing therapy for cancer are at an increased risk for …

cirrhosis
hepatitis b core antibody
entecavir
antiviral therapy
tenofovir
  • 17 views
  • 26 Apr, 2022
  • 114 locations
Prophylactic Antibiotics in Admitted Cirrhotics

In this pilot study, the investigators aim to assess feasibility of subject identification and data collection, including specimen processing, as well as the rate of enrollment for a future, larger study of the effect of empiric antibiotics for all patients with advanced cirrhosis admitted to the hospital without an existing …

antibiotics
biopsy of liver
cirrhosis
elastography
  • 0 views
  • 31 Jul, 2021
Liver Health and Metabolic Function in People With Obesity

This project aims to determine the effect of significant weight loss on rates on hepatic fibrogenesis in people with obesity.

body mass index
bariatric surgery
Accepts healthy volunteers
  • 99 views
  • 03 May, 2022
  • 1 location
Portal Vein Embolization Using Coils Plus TAGM vs Multiple Coils for Patients With Perihilar Cholangiocarcinoma or Hepatocellular Carcinoma

The aim of this study is to investigate the differences of safety and liver hypertrophy between portal vein embolization (PVE) using coils plus tris-acryl gelatin microspheres (TAGM) and multiple coils in patients with perihilar cholangiocarcinoma (pCCA) or with hepatocellular carcinoma (HCC).

chemoembolization
cholangiocarcinoma
transcatheter arterial chemoembolisation
hepatectomy
  • 0 views
  • 25 Jan, 2021
  • 1 location
The Evaluation of Surgical Decisions and Prognosis of the Radiomics and Watson Artificial Intelligence in Patients With Hepatocellular Carcinoma

The aim of this study was to evaluate the surgical decisions and prognosis of the radiomics and Watson artificial intelligence in patients with hepatocellular carcinoma.

carcinoma
hepatocellular carcinoma
  • 3 views
  • 25 Mar, 2022
  • 1 location