Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 13 clinical trials
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C3711005  

The study will evaluate the effect of coadministration of a range of doses of DGAT2i with 1 dose of ACCi, on hepatic steatosis and the ability of DGAT2i to mitigate ACCi-induced elevations in serum triglycerides. The study has a 2-part design with sequential conduct of Part 1 and Part 2 …

  • 5 views
  • 01 Aug, 2021
  • 10 locations
Effects of Long-Term Administration of Human Albumin in Subjects With Decompensated Cirrhosis and Ascites

with ascites (or with prior history of ascites requiring diuretic therapy) with or without acute-on-chronic liver failure (ACLF) at admission or during hospitalization but without ACLF at discharge.

  • 18 views
  • 25 Jul, 2021
  • 66 locations
DRAGON 1- Training Accreditation Implementation and Safety Evaluation of Combined PVE/HVE

Brief Summary: Some colorectal liver metastases can only be resected after inducing liver regeneration by portal vein embolization (PVE) to increase size function of the future liver remnant (FLR). While PVE is standard, embolization of portal vein and hepatic veins (PVE/HVE) on one side of the liver may faster and …

  • 0 views
  • 31 Jul, 2021
  • 35 locations
Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Cirrhosis;(PEGHE Trial)

Hepatic Encephaopathy is a common complication occurring in patients with Liver cirrhosis. Patients usually develop mild confusion, sleep disturbance or obtundation. It occurs due to accumulation of excess ammonia in the brain, as the liver is unable to metabolize the ammonia. The common gold standard treatment recommended for patients with …

bloating
encephalopathy
lactulose
cirrhosis
liver disease
  • 114 views
  • 18 Jul, 2021
  • 1 location
Normothermic Liver Preservation Trial

This trial is to assess the safety and efficacy of normothermic machine perfusion (NMP) as an organ preservation method prior to transplantation using the OrganOx metra device.

falling
liver transplant
metra
cold
organ preservation
  • 22 views
  • 01 Aug, 2021
  • 1 location
Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia

Hyponatremia is the most common electrolyte derangement occurring in hospitalized patients. It is usually classified as hypovolemic, euvolemic or hypervolemic. The most common aetiology of euvolemic hyponatremia is the syndrome of inappropriate antidiuresis (SIAD). Hypervolemic hyponatremia is common in patients with congestive heart failure (CHF) (10-27%) and liver cirrhosis (up …

diabetes
heart failure
vasopressin
empagliflozin
cirrhosis
  • 0 views
  • 01 Aug, 2021
  • 1 location
Tenofovir Alafenamide for the Prevention of Liver Complications in Patients With Current or Past Hepatitis B Virus Who Are Receiving Anti-Cancer Therapy for Solid Tumors

This phase III trial studies the effect of tenofovir alafenamide in preventing liver complications in patients with current or past hepatitis B virus (HBV) who are receiving anti-cancer therapy for solid tumors. People with chronic or past HBV who are undergoing therapy for cancer are at an increased risk for …

hepatitis
hepatitis b core antibody
adefovir
cancer
entecavir
  • 17 views
  • 25 Jul, 2021
  • 157 locations
Prophylactic Antibiotics in Admitted Cirrhotics

In this pilot study, the investigators aim to assess feasibility of subject identification and data collection, including specimen processing, as well as the rate of enrollment for a future, larger study of the effect of empiric antibiotics for all patients with advanced cirrhosis admitted to the hospital without an existing …

cirrhosis
elastography
antibiotics
biopsy of liver
  • 0 views
  • 31 Jul, 2021
Two-in-one Covered and Uncovered Metal Stent

Endoscopic placement of a self-expandable metal stent (SEMS) is the principle method for palliation of inoperable malignant distal biliary obstruction. However, none of bare, covered, and anti-reflux metal stent alone constantly demonstrated superiority over the others in the stent patency. To compensate for the limitations of each stent, a double …

obstruction
metastasis
biliary obstruction
reflux
  • 0 views
  • 31 Jul, 2021
  • 1 location
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Background Chronic hepatitis C infects the liver. It may scar the liver. This is called cirrhosis and may lead to liver cancer or death. Current chronic hepatitis C treatments cure most people. But some keep getting complications even after it is cured. Researchers want to study why. Objective To study …

hemophilia
fibroscan
cancer
cirrhosis
liver cancer
  • 18 views
  • 25 Jul, 2021
  • 1 location