Liver Failure Clinical Trials

A listing of Liver Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 67 clinical trials
DRAGON 1- Training, Accreditation, Implementation and Safety Evaluation of Combined PVE/HVE (DRAGON)

Brief Summary: Some colorectal liver metastases can only be resected after inducing liver regeneration by portal vein embolization (PVE) to increase size function of the future liver remnant (FLR). While PVE is standard, embolization of portal vein and hepatic veins (PVE/HVE) on one side of the liver may faster and …

  • 21 Jul, 2022
  • 27 locations
A Clinical Study of Portal Vein Embolization and Liver Venous Deprivation

The main obstacle to achieving R0 resection in future liver remnant(FLR) deficient liver cancer is the inability to retain sufficient FLR to avoid postoperative liver failure. From the initial

  • 26 Jul, 2022
  • 1 location
Effect of Preoperative Carbohydrate Loading on Post-operative Insulin Resistance After Donor Hepatectomy.

It's a randomized control trial to compare the effect of preoperative carbohydrate loading versus fasting on post operative insulin resistance after donor hepatectomy in terms of donor outcomes. Investigator will analyze the data and elucidate the value of post operative insulin resistance in reducing the occurrence of complications, length of …

Accepts healthy volunteers
  • 07 Apr, 2022
  • 1 location
The Efficacy of Oral Probiotics on Neonatal Hyperbilirubinemia

This trial will be carried out in two stages in the sick baby room of the Children's Hospital of China Medical University (CMUH). The first stage is: the enzyme active reaction kit (usually called API ZYM kit) was used to determine the β-glucuronidase activity of 9 strains of Lactobacillus and …

  • 30 Apr, 2022
  • 1 location
Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD) (PAL-LIVER)

This is a comparative effectiveness study of two pragmatic models aiming to introduce palliative care for end stage liver disease patients. The 2 comparators are: Model 1: Consultative Palliative Care (i.e. direct access to Palliative Care provider), Model 2: Trained Hepatologist- led PC intervention (i.e. a hepatologist will receive formal …

liver disease
functional assessment
  • 03 May, 2022
  • 18 locations
Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients

Early treatment of invasive fungal infections (IFI) may prevent undue mortality in acute on chronic liver failure (ACLF) patients. We aim to study the impact of early empiric treatment (based on

total parenteral nutrition
h1n1 influenza
antibiotic therapy
  • 07 May, 2022
  • 1 location
The Effects of Double Plasma Molecular Adsorption System in Acute on Chronic Liver Failure Patients

Acute liver failure patients posed high mortality rate despite receiving standard therapy. The severity and mortality even higher in patients with underlying liver disease. Acute liver failure

  • 23 Apr, 2022
  • 1 location
Pharmacokinetic Study of Icenticaftor in Participants With Hepatic Impairment

The primary purpose of this study is to evaluate the effect of hepatic impairment on the systemic pharmacokinetics, safety, and tolerability of icenticaftor in participants with varying degrees of hepatic impairment.

hepatic impairment
liver disease
Accepts healthy volunteers
  • 09 Aug, 2022
  • 1 location
A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

The main purpose of this study is to measure how much of Imlunestrant (LY3484356) gets into the bloodstream and how long it takes the body to eliminate it in female participants with impaired liver function compared to female participants with normal liver function. The side effects and tolerability of Imlunestrant …

Accepts healthy volunteers
  • 27 Jul, 2022
  • 3 locations
Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy

The purpose of the study is to evaluate the safety of Rifaximin or placebo in subjects with severe hepatic impairment and Hepatic Encephalopathy.

meld score
hepatic impairment
liver disease
  • 26 Jul, 2022
  • 21 locations