Lysosomal Acid Lipase Deficiency Lal

Lysosomal Acid Lipase Deficiency (LAL) is a rare, inherited disorder that affects the breakdown of lipids in the body. It is caused by a deficiency in the enzyme lysosomal acid lipase, which leads to the accumulation of fatty material in the liver, spleen, and other organs. Symptoms can include liver and spleen enlargement, high cholesterol and triglycerides, and cardiovascular disease.