Lupus Nephritis Clinical Trials

A listing of Lupus Nephritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 39 clinical trials
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Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

  • 926 views
  • 25 Mar, 2021
  • 12 locations
Synergetic B-cell Immunomodulation in SLE - 2nd Study.

-cell targeting by starting treatment with belimumab (anti-BAFF) followed by rituximab(anti-CD20) in lupus nephritis patients.

anti-dna antibodies
rituximab
nephritis
azathioprine
belimumab
  • 10 views
  • 07 Mar, 2021
  • 4 locations
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Pulmonary Arterial Hypertension or PAH is a progressive condition for which there is no cure. Even with substantial pharmacologic advances in the modern treatment era, survival still remains unacceptably poor, as reported in large PAH registries. Preclinical studies suggest that the administration of allogeneic CDCs have the potential to reduce …

  • 96 views
  • 25 Mar, 2021
  • 1 location
A Study of Guselkumab in Participants With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy of guselkumab in participants with active lupus nephritis (LN).

nephritis
mycophenolate
angiotensin receptor blockers
glucocorticoids
angiotensin
  • 0 views
  • 22 Apr, 2021
  • 66 locations
Safety Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.

with moderately active lupus nephritis.

nephritis
methotrexate
azathioprine
systemic lupus erythematosus
mycophenolate
  • 124 views
  • 22 Apr, 2021
  • 25 locations
A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis

This is a Phase 1b/2, multi-center study in which patients will receive KZR-616, administered as a subcutaneous (SC) injection weekly for 13 weeks (Phase 1b) or 24 weeks (Phase 2).

nephritis
antimalarial agents
systemic lupus erythematosus
corticosteroids
mycophenolic acid
  • 261 views
  • 10 May, 2021
  • 39 locations
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).

nephropathy
nephritis
proteinuria
immunoglobulin a
lupus
  • 0 views
  • 11 Jun, 2021
  • 22 locations
Study of Safety Efficacy and Tolerability of Secukinumab Versus Placebo in Combination With SoC Therapy in Patients With Active Lupus Nephritis

active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

nephritis
mammogram
urinary sediment
glomerular filtration rate
  • 37 views
  • 14 Jun, 2021
  • 108 locations
Daratumumab to Treat Active Lupus Nephritis

The purpose of this research is to study the safety and efficacy of daratumumab in inducing complete or partial remission in patients with active lupus nephritis.

remission
nephritis
proteinuria
mammogram
  • 0 views
  • 30 May, 2021
  • 1 location
The Iguratimod Effect on Lupus Nephritis (IGeLU)

This study is a 52-week, randomized, open, active-controlled trial of patients with active diffused lupus nephritis, to assess the efficacy and safety of a novel chemical synthetic agent

prednisone
nephritis
azathioprine
proteinuria
cyclophosphamide
  • 43 views
  • 22 Jan, 2021
  • 2 locations