Lupus Nephritis Clinical Trials

A listing of Lupus Nephritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
Synergetic B-cell Immunomodulation in SLE - 2nd Study. (SynBioSe-2)

-cell targeting by starting treatment with belimumab (anti-BAFF) followed by rituximab(anti-CD20) in lupus nephritis patients.

anti-dna antibodies
baff
rituximab
mycophenolate
myositis
  • 26 views
  • 27 Apr, 2022
  • 4 locations
Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis (IRIS)

The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis

nephritis
chronic kidney disease
anifrolumab
  • 7 views
  • 11 Jul, 2022
  • 18 locations
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) (SANCTUARY)

The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).

angiotensin
nephropathy
nephritis
lupus
immunosuppression
  • 5 views
  • 22 Jul, 2022
  • 62 locations
Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis (SIRIUS-LN)

This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult participants with active LN

  • 0 views
  • 10 Aug, 2022
  • 15 locations
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis (POSTERITY)

than 18 with biopsy-confirmed proliferative lupus nephritis (LN).

diphenhydramine
nephritis
mycophenolate
prednisone
mammogram
  • 0 views
  • 10 Jul, 2022
  • 18 locations
A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis (REGENCY)

) class III or IV lupus nephritis (LN) when added on to standard-of-care therapy consisting of mycophenolate mofetil (MMF) and corticosteroids.

kidney biopsy
diphenhydramine
nephritis
mycophenolate
prednisone
  • 8 views
  • 10 Jul, 2022
  • 100 locations
Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis (SELUNE)

active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

urinary sediment
nephritis
glomerular filtration rate
mammogram
  • 426 views
  • 24 Jul, 2022
  • 150 locations
Daratumumab to Treat Active Lupus Nephritis

The purpose of this research is to study the safety and efficacy of daratumumab in inducing complete or partial remission in patients with active lupus nephritis.

remission
nephritis
mammogram
proteinuria
  • 0 views
  • 06 Jun, 2022
  • 1 location
VIBRANT: VIB4920 for Active Lupus Nephritis (VIBRANT)

participants with active lupus nephritis (LN).

nephritis
mycophenolate
prednisone
  • 0 views
  • 25 Jul, 2022
  • 1 location
Zanubrutinib in Participants With Active Proliferative Lupus Nephritis

The primary objective of this study is to evaluate the efficacy of zanubrutinib added to standard of care as measured by complete renal response for participants with active proliferative lupus

  • 1 views
  • 05 May, 2022
  • 1 location