Lupus Nephritis Clinical Trials

A listing of Lupus Nephritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 43 clinical trials
Synergetic B-cell Immunomodulation in SLE - 2nd Study. (SynBioSe-2)

-cell targeting by starting treatment with belimumab (anti-BAFF) followed by rituximab(anti-CD20) in lupus nephritis patients.

nephritis
vasculitis
immunosuppressive agents
baff
anti-dna antibodies
  • 26 views
  • 27 Apr, 2022
  • 4 locations
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Pulmonary Arterial Hypertension or PAH is a progressive condition for which there is no cure. Even with substantial pharmacologic advances in the modern treatment era, survival still remains unacceptably poor, as reported in large PAH registries. Preclinical studies suggest that the administration of allogeneic CDCs have the potential to reduce …

  • 99 views
  • 25 Mar, 2021
  • 1 location
Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis (IRIS)

The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis

anifrolumab
nephritis
chronic kidney disease
  • 7 views
  • 11 Jul, 2022
  • 18 locations
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) (SANCTUARY)

The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).

nephritis
lupus
proteinuria
immunoglobulin a
nephropathy
  • 5 views
  • 22 Jul, 2022
  • 62 locations
Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis (SIRIUS-LN)

This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult participants with active LN

  • 0 views
  • 10 Aug, 2022
  • 15 locations
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis (POSTERITY)

than 18 with biopsy-confirmed proliferative lupus nephritis (LN).

prednisone
nephritis
mammogram
proteinuria
diphenhydramine
  • 0 views
  • 10 Jul, 2022
  • 18 locations
A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis (REGENCY)

) class III or IV lupus nephritis (LN) when added on to standard-of-care therapy consisting of mycophenolate mofetil (MMF) and corticosteroids.

prednisone
nephritis
mammogram
kidney biopsy
corticosteroids
  • 8 views
  • 10 Jul, 2022
  • 100 locations
Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis (SELUNE)

active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

urinary sediment
nephritis
mammogram
glomerular filtration rate
  • 426 views
  • 24 Jul, 2022
  • 150 locations
ACTHar in the Treatment of Lupus Nephritis

patients experience inflammation in the kidneys. The purpose of this study is to determine the effectiveness and safety of two dosing arms of ACTHar gel in treating proliferative Lupus Nephritis (LN). This

nephritis
kidney biopsy
cellcept
acthar
systemic lupus erythematosus
  • 330 views
  • 21 Jan, 2021
Daratumumab to Treat Active Lupus Nephritis

The purpose of this research is to study the safety and efficacy of daratumumab in inducing complete or partial remission in patients with active lupus nephritis.

mammogram
nephritis
proteinuria
remission
  • 0 views
  • 06 Jun, 2022
  • 1 location