Lupus Nephritis Clinical Trials

A listing of Lupus Nephritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 38 clinical trials
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Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

  • 926 views
  • 25 Mar, 2021
  • 12 locations
Synergetic B-cell Immunomodulation in SLE - 2nd Study.

-cell targeting by starting treatment with belimumab (anti-BAFF) followed by rituximab(anti-CD20) in lupus nephritis patients.

elisa
baff
pericarditis
nephritis
myositis
  • 10 views
  • 07 Mar, 2021
  • 4 locations
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Pulmonary Arterial Hypertension or PAH is a progressive condition for which there is no cure. Even with substantial pharmacologic advances in the modern treatment era, survival still remains unacceptably poor, as reported in large PAH registries. Preclinical studies suggest that the administration of allogeneic CDCs have the potential to reduce …

  • 96 views
  • 25 Mar, 2021
  • 1 location
A Study of Guselkumab in Participants With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy of guselkumab in participants with active lupus nephritis (LN).

kidney biopsy
nephritis
antinuclear antibody
glucocorticoids
angiotensin receptor blockers
  • 0 views
  • 01 Aug, 2021
  • 69 locations
Safety Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.

with moderately active lupus nephritis.

proteinuria
corticosteroids
nephritis
antinuclear antibody
hematuria
  • 124 views
  • 31 Jul, 2021
  • 26 locations
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).

proteinuria
nephropathy
immunoglobulin a
angiotensin
nephritis
  • 0 views
  • 08 Jul, 2021
  • 30 locations
A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis

This is a Phase 1b/2, multi-center study in which patients will receive KZR-616, administered as a subcutaneous (SC) injection weekly for 13 weeks (Phase 1b) or 24 weeks (Phase 2).

treatment regimen
kidney biopsy
nephritis
antinuclear antibody
immunosuppressive agents
  • 261 views
  • 10 May, 2021
  • 39 locations
Study of Safety Efficacy and Tolerability of Secukinumab Versus Placebo in Combination With SoC Therapy in Patients With Active Lupus Nephritis

active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

urinary sediment
mammogram
nephritis
glomerular filtration rate
  • 37 views
  • 30 Jul, 2021
  • 123 locations
Daratumumab to Treat Active Lupus Nephritis

The purpose of this research is to study the safety and efficacy of daratumumab in inducing complete or partial remission in patients with active lupus nephritis.

proteinuria
remission
mammogram
nephritis
  • 0 views
  • 30 May, 2021
  • 1 location
ACTHar in the Treatment of Lupus Nephritis

patients experience inflammation in the kidneys. The purpose of this study is to determine the effectiveness and safety of two dosing arms of ACTHar gel in treating proliferative Lupus Nephritis (LN). This

systemic lupus erythematosus
cellcept
acthar
kidney biopsy
nephritis
  • 71 views
  • 21 Jan, 2021