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Inflammatory Bowel Disease Clinical Trials

A listing of Inflammatory Bowel Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (531) clinical trials

Evaluation of 3D Visualization for Total Colectomy

Three-dimensional (3D) visualization technology for laparoscopy has been proposed, since the early 1990's, as a method to facilitate laparoscopic performance. However, early 3D laparoscopic technology was limited in terms of image quality, so that its use had not been implemented. The latest technical developments ensure high-definition 3D visualization with the ...

Phase N/A

Faecal Bacteriotherapy for Ulcerative Colitis

The etiopathogenesis of ulcerative colitis (UC) is not fully understood. One of the theories of UC pathogenesis represents a pathological response of mucosal immunity to intestinal microbiota. Potential therapeutic procedure how to affect this fact is the faecal microbiota transplantation (FMT). Review of the literature on FMT suggests great potential ...


Assessing the Tolerability of Oligosaccharide Supplementation in Patients With Crohn's Disease

Subjects age >/= 19 years with the diagnosis of CD for >/= 6 months, currently in remission based on the Harvey-Bradshaw Index score (</=4 points) and C-reactive protein (<5 mg/L) will be recruited from two academic hospitals and affiliated gastroenterology outpatient clinics (St. Paul's Hospital, Vancouver, British Columbia, Canada; Alfred ...

Phase N/A

Capsule Endoscopy in Inflammatory Bowel Disease (IBD) in Children

There is growing concern with recurrent radiation exposure particularly from routine radiologic modalities in children, this is especially relevant in pediatric Crohn's Disease in so far as CT entercolysis abdomen and small bowel series are often seen as complementary. Although small bowel series is accepted as a routine diagnostic modality ...

Phase N/A

The Challenge Study: A Dietary Personalization Protocol for Patients With Crohn's Disease and Deep Remission

The investigators have previously hypothesized that Crohn's disease may occur via a sequence of events involving dysbiosis and genetically determined or environmentally acquired defects in innate immunity, and have further hypothesized that the mechanism of EEN for induction of remission acts by reducing exposure to dietary components that may cause ...

Phase N/A

Analysis of Volatile Organic Compounds in the Exhaled Air in Inflammatory Bowel Disease

Background: The diagnosis and differentiation of inflammatory bowel diseases (IBD) is challenging due to the absence of a gold standard diagnostic modality for confirmation. Exhaled breath volatile metabolite analysis focusing on diagnosis and differentiation of IBD is a promising approach. Thus, the aim of this study is to evaluated the ...

Phase N/A

Autologous Stem Cell Transplant for Crohn's Disease

Crohn's Disease Inflammatory bowel disease, encompassing Crohn's disease (CD) and ulcerative colitis (UC), represent incurable chronic inflammatory disorders of the intestinal tract. Patients with IBD experience a chronic relapsing and remitting course of their disease, with little ability to predict when these flares will occur. The primary symptoms of IBD ...


COmparison of MicroBiota AccordIng to Age in Crohn's Disease (COMeBACk)

The primary aim is to describe by principal component analysis and compare the gut microbiota between subgroups of paediatric-onset (n=75), elderly-onset CD patients (n=75) and control subjects (75 paediatric control and 75 elderly control subjects matched on age) without an a priori approach of high throughput sequencing of bacterial DNA. ...

Phase N/A

NKT Role in the Regulation of the Inflammatory Bowel Disease

Inflammatory bowel diseases (IBD) include Crohn's disease (CD) and ulcerative colitis (UC). These diseases are a public health problem because they concern many patients (1 case in 1000). IBDs are characterized by dysregulated immune response against luminal antigens causing chronic inflammation of the gut in genetically predisposed individuals. Their exact ...

Phase N/A

Mercaptopurine Therapy in Ulcerative Colitis

Subjects will receive treatment with oral prednisone 40 mg/day for 2 weeks, followed by fixed tapering over 6 weeks. Half of the subjects will be randomized to concomitant 6-MP 1-1.5 mg/kg/day and half will receive concomitant placebo treatment. During the entire course of the trial all subjects will receive maintenance ...