Inflammatory Bowel Disease Clinical Trials

A listing of Inflammatory Bowel Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 355 clinical trials
An Open-label, Multi-center Extension Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Moderate to Severe Crohn's Disease or Moderate to Severe Ulcerative Colitis

The purpose of this study is to evaluate the long-term safety and efficacy of Deucravacitinib in participants who have previously been enrolled in a Deucravacitinib Phase 2 study for moderate to severe Crohn's disease or moderate to severe Ulcerative Colitis.

colitis
ulceration
crohn's disease
ulcerative colitis
  • 0 views
  • 27 Oct, 2022
  • 22 locations
Ileal Crohn's Disease and Post-operative Outcome: Prospective Cohort Study of the REMIND Group (POP-REMIND)

Crohn's disease (CD), a chronic inflammatory process in intestinal segments leads to tissue damage. More than two thirds of CD patients need intestinal resection. Symptomatic clinical recurrence occurs in 60% by 10 years. The principal factors affecting postoperative recurrence are active smoking, penetrating disease, perianal lesions history, prior intestinal resection, …

mercaptopurine
tumor necrosis factor
crohn's disease
bowel resection
thiopurines
  • 9 views
  • 27 Feb, 2022
  • 12 locations
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

This study proposes a randomized prospective study comparing the Kono-S anastomosis to the standard side-to-side anastomosis.This will be a multi-center randomized prospective trial. Patients with Crohn's ileitis or Crohn's ileocolitis requiring resection will be randomized to undergo either the Kono-S anastomosis or the side-to-side functional end anastomosis.

tumor necrosis factor
ileocolitis
tumor necrosis factor alpha
tumour necrosis
ileitis
  • 14 views
  • 14 Apr, 2022
  • 12 locations
A Phase 3, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of Darvadstrocel in the Treatment of Complex Perianal Fistula in Pediatric Subjects With Crohn's Disease Over a Period of 24 Weeks and an Extended Follow-up Period for a Total of up to 52 Weeks

A perianal fistula is an abnormal passageway that develops between the rectum and the skin near the anus. The fistula is considered complex if it branches into several openings or an abscess is also present. The main aim of this study is to learn if complex perianal fistulas in children …

methotrexate
mercaptopurine
azathioprine
corticosteroids
crohn's disease
  • 0 views
  • 21 Oct, 2022
  • 22 locations
Induction Study #2 - A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

corticosteroids
endoscopy
crohn's disease
ileal disease
abdominal pain
  • 550 views
  • 22 Oct, 2022
  • 357 locations
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a study to demonstrate the effect of oral ozanimod as maintenance therapy in participants with moderately to severely active Crohn's Disease.

crohn's disease
abdominal pain
remission
  • 1028 views
  • 22 Oct, 2022
  • 490 locations
A Phase 3, Multicenter, Open-Label, Long-Term Extension Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Patients With Crohn's Disease (VIVID-2)

The reason for this study is to determine the long-term efficacy and safety of the study drug mirikizumab in participants with Crohn's disease.

crohn's disease
  • 47 views
  • 24 Oct, 2022
  • 282 locations
A Phase 3, Multicenter, Open-Label Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is an extension study to evaluate safety and efficacy of ozanimod in participants with moderately to severely active Crohn's Disease.

crohn's disease
remission
  • 1144 views
  • 18 Oct, 2022
  • 502 locations
A Phase 3 Study of the Efficacy, Safety, and Pharmacokinetics of Ustekinumab as Open-label Intravenous Induction Treatment Followed by Randomized Double-blind Subcutaneous Ustekinumab Maintenance in Pediatric Participants With Moderately to Severely Active Crohn's Disease (UNITI Jr)

The purpose of this study is to evaluate the efficacy of ustekinumab dosing in inducing clinical remission (Global) and in maintaining clinical remission (US); to evaluate the safety profile and ustekinumab exposure (pharmacokinetics [PK]) in pediatric participants with moderately to severely active Crohn's disease.

fistulising crohn's disease
remission
ustekinumab
colitis
ileitis
  • 0 views
  • 20 Oct, 2022
  • 42 locations
Induction Study #1 - A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

corticosteroids
endoscopy
crohn's disease
ileal disease
abdominal pain
  • 918 views
  • 25 Oct, 2022
  • 387 locations