Limb Spasticity Clinical Trials

A listing of Limb Spasticity medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 22 clinical trials
A Study to Compare the Safety and Efficacy of Dysport and Botox in Adults With Upper Limb Spasticity.

This study is aiming to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as the primary safety endpoint, and the superiority of aboBoNT-A over onaBoNT-A with respect to duration of response as the key secondary efficacy endpoint when used at optimal doses according to approved prescribing information of each …

  • 0 views
  • 22 Jul, 2021
  • 1 location
A Study to Assess the Safety and Efficacy of IPN10200 of in Adult Participants With Upper Limb Spasticity.

The purpose of the study is to assess the safety and efficacy of increasing doses of IPN10200 with the aim to evaluate the Pharmacodynamics (PD) profile of IPN10200 and to establish the total IPN10200 doses(s) that offer the best efficacy/safety profile when used for the treatment of Adult upper limb …

  • 0 views
  • 30 Jul, 2021
  • 31 locations
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

limb spasticity caused by stroke or traumatic brain injury (Main Period). Participants will be assigned to the treatment groups by chance and neither the participants nor the research staff who

  • 19 views
  • 04 Aug, 2021
  • 61 locations
Efficacy and Safety Study of MYOBLOC in the Treatment of Adult Lower Limb Spasticity

Multicenter, randomized, double-blind, placebo-controlled study of the safety and efficacy of single-dose MYOBLOC over a 1-year duration in adult subjects with lower limb spasticity, followed by

hemiplegia
stroke
traumatic brain injury
myobloc
  • 0 views
  • 25 Jul, 2021
  • 4 locations
Home Based Electrical Stimulation on Post-stroke Lower Limb Tightness.

lower limb spasticity in patient with post-stroke more than 6 months and to assess the impact of the program. This is single arm prospective intervention study. Patient will apply home-based NMES on

  • 0 views
  • 28 Jun, 2021
  • 1 location
Goal Attainment Scaling in Upper Limb Spasticity Treatment

Patients after stroke with upper limb spasticity treated with botulinum toxin-A (BTX-A) will be included in this two-part study. In the first part, goal attainment scaling and comprehensive

  • 0 views
  • 30 Jul, 2021
  • 1 location
The Feasibility and Effects of Low-load Blood-flow Restricted Exercise Following Spinal Cord Injury

Spinal cord injury (SCI): The World Health Organization estimates an incidence of 250,000 to 500,000 per year worldwide. In Denmark 130 new cases of SCI per year. SCI is a devastating condition: paresis/paralysis of the skeletal muscles below the injury site, partial or complete inability to walk, move and/or feel. …

nephrologic disease
spasticity
spinal cord
spinal cord disorder
strength training
  • 32 views
  • 17 Jun, 2021
  • 1 location
A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes

The purpose of this study is to improve the performance of neuroprosthesis for standing after SCI by developing and testing new advanced methods that use multiple contact peripheral nerve electrodes to slow the onset of fatigue and increase standing duration. The new advanced methods will take advantage of the ability …

spasticity
muscle spasm
spinal cord
spinal cord disorder
spasm
  • 174 views
  • 28 Jan, 2021
  • 1 location
A Neuroprosthesis for Seated Posture and Balance

The purpose of this study is to evaluate a surgically implanted functional electrical stimulation (FES) system to facilitate stability of the trunk and hips. FES involves applying small electric currents to the nerves, which cause the muscles to contract. This study evaluates how stabilizing and stiffening the trunk with FES …

spasticity
spinal cord
spinal cord disorder
spasm
electrical stimulation
  • 225 views
  • 20 May, 2021
  • 1 location
Transspinal Stimulation Plus Locomotor Training for SCI

Locomotor training is often used with the aim to improve corticospinal function and walking ability in individuals with Spinal Cord Injury. Excitingly, the benefits of locomotor training may be augmented by noninvasive electrical stimulation of the spinal cord and enhance motor recovery at SCI. This study will compare the effects …

  • 0 views
  • 28 Mar, 2021
  • 2 locations