Genitourinary Cancer Clinical Trials

A listing of Genitourinary Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 226 clinical trials
A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

This study will test an experimental drug (enfortumab vedotin) alone and with different combinations of anticancer therapies. Pembrolizumab is an immune checkpoint inhibitor (CPI) that is used to treat patients with cancer of the urinary system (urothelial cancer). This type of cancer includes cancer of the bladder, renal pelvis, ureter …

chemoradiation
radical cystectomy
combinations
metastatic cancer
bcg vaccine
  • 284 views
  • 23 Jul, 2021
  • 93 locations
Impact of Remimazolam on Prognosis After Bladder Cancer Surgery

Bladder cancer is one of the most common genitourinary cancers. Transurethral resection of bladder tumor (TURBT) is the standard therapy for nonmuscle invasive bladder cancer. However, patients

invasive bladder cancer
bladder tumor
surgery for bladder cancer
transurethral resection
transurethral bladder excision
  • 0 views
  • 19 Jul, 2021
  • 6 locations
Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Background Genitourinary cancers are some of the most common types of cancer. They are lethal when they spread. The drug M7824 blocks the paths that cancer cells

nhs-il12
measurable disease
neutrophil count
metastatic cancer
entecavir
  • 0 views
  • 29 Jul, 2021
  • 1 location
Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

This research study is studying a combination of drugs as a possible treatment for rare genitourinary malignancies among four cohorts, bladder or upper tract carcinoma with variant histology, adrenocortical carcinoma, other rare genitourinary carcinomas and any genitourinary carcinoma with neuroendocrine differentiation. Given preliminary results, the study is being tested in …

carcinoma
platelet count
neutrophil count
measurable disease
adenocarcinoma of the prostate
  • 81 views
  • 17 Jul, 2021
  • 6 locations
Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

This trial studies how well tucatinib works for solid tumors that make either more HER2 or a different type of HER2 than usual (HER2 alterations) The solid tumors studied in this trial have either spread to other parts of the body (metastatic) or cannot be removed completely with surgery (unresectable). …

metastatic cervical cancer
hormone therapy
measurable disease
HER2
trastuzumab
  • 0 views
  • 01 Aug, 2021
  • 21 locations
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

This study will investigate the effects of atezolizumab on select cancer types in people whose analysis of tumour DNA and RNA indicates they may be sensitive to atezolizumab. This study aims to determine if the information from the cancer genome analysis corresponds with the effects of atezolizumab on individuals and …

platelet count
measurable disease
neutrophil count
granulocyte colony stimulating factor
metastatic cancer
  • 0 views
  • 23 Jul, 2021
  • 1 location
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. …

hormone therapy
major surgery
platelet count
ipilimumab
neutrophil count
  • 191 views
  • 01 Aug, 2021
  • 474 locations
Malignant Genito-urinary Tumors in Children: South Egypt Cancer Institute Experience

The aim of this study is to identify demographic & disease characteristics in pediatric oncology patients diagnosed with one of genitourinary tumors & treatment outcomes in these patients.

  • 6 views
  • 31 Jul, 2021
  • 1 location
Rapid Autopsy and Procurement of Cancer Tissue

Background Individuals with cancer of the lung, chest cavity, ovary, or bladder, as well as patients who have been treated with adoptive cell therapy unfortunately commonly succumb to their disease. Some agree to donate their bodies to cancer research that may help the medical community better understand these diseases. Studies …

carcinoma
cavity
lung carcinoma
urothelial carcinoma
thymoma
  • 44 views
  • 29 Jul, 2021
  • 1 location
(CLONEVO): Cell cycLe inhbitiON to Target the EVolution of UrOthelial Cancer

Single-arm, open-label window-of-opportunity trial of neoadjuvant Abemaciclib in 20 patients, with tumor tissue obtained as standard of care at tumor resection (pre-Abemaciclib) and cystectomy (post-Abemaciclib)

transitional cell carcinoma
radical cystectomy
carcinoma
neutrophil count
white blood cell count
  • 16 views
  • 26 Jul, 2021
  • 3 locations