Myositis Clinical Trials

A listing of Myositis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 47 clinical trials
Pompe & Pain - Study to Assess Nociceptive Pain in Adult Patients With Pompe Disease

The primary aim of this nationwide, explorative, cross-sectional study in Germany is to characterize the prevalence, severity and quality of musculoskeletal pain in adult patients with late-onset Pompe disease (LOPD). The secondary objectives are to evaluate whether muscle pain is associated with muscle function, to assess whether muscle pain is …

exercise tests
inclusion body myositis
  • 04 Oct, 2022
  • 1 location
The Pathogenesis of Depression - Possible Autoimmune Mechanisms

' syndrome (SS), systemic sclerosis (SSc), inflammatory myopathies (IIM), any Overlap of the above including mixed connective tissue disease (MCTD), systemic vasculitis (see Chapel Hill classification

progressive systemic sclerosis
depressed mood
depressive symptoms
  • 09 Apr, 2022
  • 1 location
Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) (CDASI)

The Evaluation of Clinical Responsiveness Using the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), established in 2008, is a one-site database study conducted at the University of Pennsylvania. The database has yielded valuable information and clinical insights into the pathophysiology, disease processes, including psychological responses, treatments and quality of …

  • 23 Mar, 2022
  • 1 location
PRediction Of DIverse Glucocorticoids toxIcity OUtcomeS (PRODIGIOUS)

To date, there is no available tool that allows, at individual level, determination of the probability to develop clinically relevant complications of prolonged glucocorticoid therapy. In patients with inflammatory rheumatic disorders requiring prolonged glucocorticoid therapy, such tool could be useful to adapt first-line treatment decisions (in daily practice and in …

glucocorticoid therapy
  • 26 May, 2022
  • 9 locations
ILD-SARDs Registry and Biorepository

A complex interaction between demographic, environmental and genetic mechanisms impact the onset, severity and outcome of ILD-SARDs through dysregulation of the immune system and lung pro-biotic pathways. Comorbidity and genetic risk indicate that there are overlapping pathogenic mechanisms among SARDs, some of which underlie ILD in different SARDs. The purpose …

bronchoalveolar lavage
lung disease
connective tissue disease
chest ct
  • 18 Sep, 2021
  • 1 location
Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

ICI's have become the first-line treatment for patients with various malignancies. Although case studies represent fulminant myocarditis, there is uncertainty in prevalence of subclinical myocardial injury induced by ICI's. In this prospective study, ICI treatment naïve patients with no significant prior cardiovascular history were enrolled. Primary outcome was the prevalence …

heart failure
  • 12 May, 2022
  • 1 location
The Clinical Course of Interstitial Pneumonia With Autoimmune Features

Interstitial pneumonia with autoimmune features (IPAF) is a chronic interstitial lung disease (ILD) with some laboratoristic and/or clinical features of autoimmune disease, but without meeting criteria of connective tissue disease (CTD), and with no other causes of ILD. Despite recent efforts to standardize the diagnosis of IPAF, subjects with IPAF …

lung transplant
  • 20 Apr, 2022
  • 1 location