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Myositis Clinical Trials

A listing of Myositis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (30) clinical trials

Study of Pioglitazone in Sporadic Inclusion Body Myositis

This is a 52-week, Phase 1, open-label, single center, proof of concept study of FDA-approved pioglitazone in adult patients with sporadic inclusion body myositis (sIBM). The trial consists of a 4-week screening period;16-week "lead-in" period during which all subjects are observed off-treatment. At Week 16, all subjects will be started ...


Physical Training in Patients With Idiopathic Inflammatory Myopathies

To assess the impact of 12-weeks of physical training in patients with idiopathic inflammatory myopathies.

Phase N/A

MYOPROSP - a Prospective Cohort Study in Myositis

The bioresource from this protocol, ethics application and future funding will comprise the following i) UKMYONET cross-sectional study ii) MYOPROSP inception cohort study iii) MYOACT novel therapies registry iv) UK neuromuscular biobank Primary endpoint The primary study endpoint will be sensitivity to change of the biomarkers of interest. Secondary endpoints ...

Phase N/A

Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis

I. Objective 18-kDa translocator protein (TSPO) and cyclooxygenase-2 (COX-2) are both implicated in the pathophysiology of various inflammatory disorders, suggesting that both may serve as potential biomarkers of inflammation in brain as well as periphery. Our laboratory recently developed two new radioligands: [11C]ER176 to image TSPO and [11C]MC1 to image ...


Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.

Phase N/A

Influence of Aerobic Training and Weight Loss on Skeletal Muscle Inflammatory Markers and Muscle Protein Balance in Older Adults

It is estimated that 15% of adults aged 60-70 years, and up to 50% of adults aged 80 years and older are affected by sarcopeniathe age related loss of muscle mass and function. A disruption of the homeostatic balance between periods of muscle protein breakdown (predominant during fasting) and muscle ...

Phase N/A

Establishing Muscle Impedance Parameters With Electrical Impedance Myography

In this pilot study, the electrical impedance myography (EIM) parameters of individuals with inclusion body myositis (IBM) will be compared with age and sex matched normal data. Along with EIM parameters, clinical outcome measures will be obtained to understand how EIM data correlates with these parameters. A focused study to ...

Phase N/A

Comparison Between CT and MRI in Preoperative Evaluation of Neurogenic Myositis Ossificans or Neurogenic Para-osteo-arthritis

This is a study on diagnostic performance, non randomized, versus Gold standard (a prospective multicentric cohort). All eligible patients will be proposed consecutively to participate to the study, to undergo preoperative CT scan and MRI examination as usual procedure. The only additional action in this study will be a neurography ...

Phase N/A

Feasibility of a Blended Therapy Approach

Myositis and haemophilia belong with a prevalence rate of 0.4-17.3 of 100`000 and 2-12 of 100`000, respectively to the group of RDs. The fact that a RD affects only a small number of people, indicates that rehabilitation knowledge outside the specialised medical centers is rare. Thus, since many people with ...

Phase N/A

Elastography in Patients With Idiopathic Inflammatory Myopathies

This study will be carried out on four groups: Group (I): thirty children diagnosed to have idiopathic inflammatory myopathies(IIM) Group (II): thirty adults diagnosed to have IIM Group (III):20 healthy children matching age and sex as first control group to children with IIM . Group (VI):20 healthy adults matching age ...

Phase N/A