Myositis Clinical Trials
A listing of Myositis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 47 clinical trials
Exercise Capacity of Patients With Dermatomyosis
Dermatomyositis (DM) patients experience muscle weakness and low aerobic capacities, which are associated with poor health status and increased mortality. The origin of this muscle impairment remains unknown. The investigators hypothesize that mitochondria functioning is impaired in DM muscle and links with exercise capacities.
- 0 views
- 04 Oct, 2022
- 1 location
A Phase Ib Study of Nivolumab in Patients With Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's …
- 995 views
- 28 Oct, 2022
- 33 locations
Immunosuppressant Combined With Pirfenidone in CTD-ILD
A prospective cohort study was used to observe the efficacy and safety of different immunosuppressive agents with/wo pirfenidone on CTD-ILD patients in Qilu Hospital of Shandong University for 36 months.The main research endpoints are lung function, patient dyspnea score, 6-minute walking distance, imaging indicators, primary disease activity, adverse reactions, etc.
- 2 views
- 24 Jun, 2021
- 1 location
Efficacy,Immune Function of Pirfenidone in the Treatment of Connetive Tissue Disease -Ralated Interstitial Lung Disease(CTD-LID)
A single-center randomized controlled study was used to observe the efficacy and immune function with/wo pirfenidone on CTD-ILD patients in QIlu Hospital of Shanndong University for 24 months. 2:1 randomization was performed。The main research endpoints are lung function.
- 0 views
- 17 Oct, 2022
- 1 location
AbataCept for the Treatment of Immune-cHeckpoint Inhibitors Induced mYocarditiS (ACHLYS)
Immune-checkpoint-inhibitors (ICI) have revolutionized treatment for 20 cancer types. They unleash anti-tumor immune responses. Unfortunately, in 0.36-1.23% of patients, this activation can also lead to lethal immune-related adverse events (irAEs) that can affect any organ. Among those irAEs, ICI-induced myocarditis are the most frequently fatal with death rate reaching 50% …
- 0 views
- 20 Oct, 2022
- 1 location
The Fibrodysplasia Ossificans Progressiva (FOP) Connection Registry
The Fibrodysplasia Ossificans Progressiva (FOP) Connection Registry is a global, non-interventional, voluntary database that captures demographic and disease data directly from FOP patients and their caregivers via a secure, web-based patient portal. A physician portal (in development) will allow physicians to enter clinical data about their patients. The objectives are …
- 44 views
- 21 Jan, 2021
- 1 location
Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies
inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability. Children or adults with polymyositis or dermatomyositis or a related condition may be
- 166 views
- 22 Oct, 2022
- 4 locations
Clinical Database and Biobank of Patients With Inflammatory Myopathies: the MASC Project (Myositis DNA Serum Cells) (MASC)
Myositis are rare diseases for which the development of a cohort associated with a bank of biological samples (biobank) will allow for the conduct of researches to better delineate the
- 0 views
- 09 Sep, 2021
- 2 locations
Study and Treatment of Inflammatory Muscle Diseases
This study of inflammatory muscle diseases-polymyositis and dermatomyositis and related disorders-will examine what causes these diseases and describe the clinical features (signs and symptoms
- 844 views
- 09 Apr, 2023
- 1 location
Investigating Genes in Patients With Polymyositis and Dermatomyositis
Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM)belong to a group of inflammatory muscle disorders, of unknown cause, that are characterised by skeletal muscle
- 105 views
- 29 Sep, 2021
- 1 location