Myositis Clinical Trials

A listing of Myositis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 47 clinical trials
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of IgPro20 in Adults With Dermatomyositis (DM) (RECLAIIM)

This is a phase 3, multicenter, randomized, placebo-controlled, double-blind study of IgPro20 (subcutaneous Ig) treatment in adult subjects with dermatomyositis (DM). The primary objective of this study is to assess the efficacy of IgPro20 subcutaneous (SC) doses in comparison to placebo in adult subjects with DM, as measured by responder …

rash
dermatomyositis
rheumatism
corticosteroids
prednisolone
  • 38 views
  • 09 Apr, 2023
  • 51 locations
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies (SPIREA)

The purpose of this study is to evaluate the efficacy and safety of Nipocalimab versus placebo in participants with active idiopathic inflammatory myopathies (IIM).

dermatomyositis
myopathy
tacrolimus
prednisone
  • 0 views
  • 16 Oct, 2022
  • 2 locations
Search for Diagnostic and Prognostic Biomarkers in Systemic Sclerosis and Inflammatory Myopathies

Systemic sclerosis and inflammatory myopathies, which sometimes combine (scleromyositis), have shared pathophysiological elements. In both diseases, many cell subtypes are involved in damage to

scleroderma
raynaud's phenomenon
muscle biopsy
myopathy
raynaud's syndrome
  • 0 views
  • 23 Dec, 2021
  • 1 location
Evaluation of Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis

18 and older with rheumatoid arthritis or idiopathic inflammatory myopathy (IIM). Healthy volunteers enrolled in protocol 01-M-0254 or 17-M-0181 are also needed. Design

weakness
x-rays
steroidal anti-inflammatory drugs
myositis
nonsteroidal anti-inflammatory drugs
  • 46 views
  • 22 Oct, 2022
  • 1 location
A Phase 1 Study of ABC008 in Adult Patients With Inclusion Body Myositis (IBM)

An open-label, ascending dose study for adult patients with inclusion body myositis (IBM).

inclusion body myositis
  • 2 views
  • 05 Mar, 2022
  • 4 locations
Clinical Study of MMF in Treatment of IIM-ILD and Its Effect on Peripheral Blood Treg Cells

Interstitial lung disease (ILD) is a common pulmonary manifestation of idiopathic inflammatory myopathy (IIM). The overall 5-year mortality is 50%. The prognosis is poor and the treatment is

lupus
interstitial lung disease
myopathy
vasculitis
cyclosporine
  • 0 views
  • 30 Nov, 2021
  • 1 location
A Double-Blind Randomised Controlled Trial (dbRCT) Phase III Trial Investigating the Effect of Sirolimus on Disease Progression in Patients With Inclusion Body Myositis (IBM) as Measured by the IBM Functional Rating Scale (IBM-FRS)

The hypothesis is that Sirolimus, (Rapamycin (R)) which is currently used in organ transplantation and works by blocking the activity of T effector cells but preserving T regulatory cells, as well as by inducing autophagy (protein degradation), will be effective in IBM to slow or stabilize disease progression, helping to …

immunosuppression
  • 0 views
  • 23 Oct, 2022
  • 3 locations
Cell Therapy for IBM by Muscle Injection of ADSVF (ADSVF-in-IBM)

Inclusion Body Myositis is a slowly but disabling myopathy, the most frequent in patients over 50 years old. No treatments (in particular immunosuppressive) are known to be efficient.

  • 0 views
  • 04 Apr, 2023
An Open-label Study of Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis

Background Dermatomyositis (DM) and juvenile dermatomyositis (JDM) cause inflammation in the muscles. People with DM and JDM can develop calcium deposits in places they should not, known as calcinosis. Calcinosis can be painful and cause disabilities and other problems. Researchers want to learn more about calcinosis to find treatments for …

aldolase
diabetes
myositis
blood tests
calcium
  • 190 views
  • 22 Oct, 2022
  • 1 location
Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease

"Antisynthetase syndrome (ASS) is one of the most severe inflammatory myopathy (IM), due to pulmonary involvement (interstitial lung disease, ILD). Until now, the most commonly used

  • 1 views
  • 15 Feb, 2021
  • 1 location